ArticleFrontiers in neurology
Predictive value and correlation analysis of neutrophil-to-lymphocyte ratio for early prognosis in patients with intracerebral hemorrhage undergoing surgical treatment.
Article in Frontiers in neurology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: Intracerebral hemorrhage (ICH) represents a fatal acute neurological condition. Neutrophil-to-lymphocyte ratio's (NLR) early prognostic value in surgical ICH needs validation. Objective: This study explored and quantified the early postoperative predictive value of NLR in surgically treated ICH patients. Methods: Retrospective data of 74 surgically treated ICH patients at The Affiliated Hospital of Xuzhou Medical University from November 2023 to September 2024 were collected, with 70 enrolled after exclusion. The primary endpoint was 30-day postoperative poor functional outcome [modified Rankin Scale (mRS) 4-6], and postoperative day 3 NLR (NLR-D3) was defined as the core predictive biomarker; secondary outcome was in-hospital complication incidence. All patients were stratified by 30-day mRS into good prognosis (mRS 0-3, Results: The poor prognosis group had older age, lower admission Glasgow coma scale scores, larger hematoma volumes, and higher rates of intraventricular extension and midline shift (all Conclusion: For surgically treated ICH patients, early postoperative elevated NLR, especially on day 3, correlates closely with adverse outcomes, acting as an inflammatory indicator for short-term poor prognosis.
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