Evidence map›Paper›PMID 42488338›Full record

ArticleExperimental and therapeutic medicine2026

Role and insights of human papillomavirus E5 oncoprotein in cervical carcinogenesis.

Jyoti Rani, Sandeep Sisodiya, Kapil Kumar, Sandeep Kumar, Asiya Khan, Ekta Gupta, Showket Hussain

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Experimental and therapeutic medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jyoti RaniHPV Diagnostics, Research and Innovation Laboratory, ICMR-National Institute of Cancer Prevention and Research, Noida, Uttar Pradesh 201301, India.
Sandeep SisodiyaHPV Diagnostics, Research and Innovation Laboratory, ICMR-National Institute of Cancer Prevention and Research, Noida, Uttar Pradesh 201301, India.
Kapil KumarDepartment of Zoology, Meerut College, C.C.S. University, Meerut, Uttar Pradesh 250001, India.
Sandeep KumarHPV Diagnostics, Research and Innovation Laboratory, ICMR-National Institute of Cancer Prevention and Research, Noida, Uttar Pradesh 201301, India.
Asiya KhanMultidisciplinary Research Unit, Government Institute of Medical Sciences, Greater Noida, Uttar Pradesh 201310, India.
Ekta GuptaDivision of Clinical Oncology, ICMR-National Institute of Cancer Prevention and Research, Noida, Uttar Pradesh 201301, India.
Showket HussainHPV Diagnostics, Research and Innovation Laboratory, ICMR-National Institute of Cancer Prevention and Research, Noida, Uttar Pradesh 201301, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cervical cancer is a highly prevalent malignancy affecting the health of women, and a leading cause of cancer-related mortality worldwide, particularly in low- and middle-income countries. The primary cause of cervical is persistent infection with high-risk human papillomavirus (HPV), particularly through the activation of its oncoproteins E6 and E7 that interact with host tumor suppressor genes. Another HPV oncoprotein, E5, has been reported to alter several tumorigenic signaling pathways; however, its precise role in cervical cancer has not yet been fully elucidated. Therefore, the aim of the present study was to perform a comprehensive

Indexed as

cervical cancerdifferentially expressed genesE5 oncoproteinhub geneshuman papillomavirusprotein-protein interaction

Identifiers

PMID42488338
PMCPMC13389621

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.