Observational studyThe Iowa orthopaedic journal2026
Reliability of Semi-Automated Volumetric Quantification of Knee Effusion Using MRI After Acl Injury.
Observational study in The Iowa orthopaedic journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
Background: Effusion is a frequent finding after anterior cruciate ligament (ACL) injury and reconstruction, but the reliability of its quantification on routine [non-contrast] magnetic resonance imaging (MRI) is not established. This study sought to evaluate the intra-rater and inter-rater reliability of volumetric quantitative measurements (VQM) of knee effusion volumes (EV) using axial proton density-weighted, fat-suppressed (PD-FS) sequences after ACL injury and reconstruction. Methods: Twenty deidentified MRIs (10 ACL-injured knees and 10 uninjured knees) were randomly selected from a prospective observational cohort of participants aged 15-35 years. Two independent raters analyzed EV using a custom MATLAB protocol. Intra- and inter-rater reliability was assessed using intraclass correlation coefficients (ICC Results: Mean EV were higher in the injured compared to uninjured knees (11.88±8.14 mL vs 2.03±0.76 mL). Volumetric effusion measurements demonstrated excellent intra-rater (ICC Conclusion: VQM using standard axial PD-FS MRI sequences demonstrate excellent reliability across raters. Restricting segmentation to the anterior compartment aligns with clinical assessment (e.g., sweep tests), though it does not capture whole-joint eflusion. This semi-automated approach may provide a relevant biomarker for monitoring EV in ACL research and rehabilitation trials. Level of Evidence: III.
Indexed as
Identifiers
42488317PMC13389605What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.