Evidence map›Paper›PMID 42488141›Full record

ArticleHeart rhythm O22026

Characteristics, pathophysiological mechanisms, and ablation outcomes of patients with de novo left atrial flutter compared with patients with postablation left atrial flutter.

Valon Spahiu, Thomas Kueffer, Ruben Fuentes Artiles, Berat Gerguri, Salik Ur Rehman Iqbal, Antonio Madaffari, Gregor Thalmann, Claudia Herrera, Boldizsar Kovacs, Nikola Kozhuharov and 7 more

Abstract read
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In one paragraph

Article in Heart rhythm O2, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Valon SpahiuDepartment of Cardiology, Inselspital - University Hospital Bern, University of Bern, Bern, Switzerland.
Thomas KuefferDepartment of Cardiology, Inselspital - University Hospital Bern, University of Bern, Bern, Switzerland.
Ruben Fuentes ArtilesDepartment of Cardiology, Inselspital - University Hospital Bern, University of Bern, Bern, Switzerland.
Berat GerguriDepartment of Internal Medicine, Salem Hospital, Bern, Switzerland.
Salik Ur Rehman IqbalDepartment of Cardiology, Inselspital - University Hospital Bern, University of Bern, Bern, Switzerland.
Antonio MadaffariUnità operativa cardiologia indirizzo elettrofisiologia, Ospedale Santa Maria del Carmine di Rovereto, Trentino-Alto Adige, Italy.
Gregor ThalmannDepartment of Cardiology, Inselspital - University Hospital Bern, University of Bern, Bern, Switzerland.
Claudia HerreraDepartment of Cardiology, Inselspital - University Hospital Bern, University of Bern, Bern, Switzerland.
Boldizsar KovacsDepartment of Cardiology, Inselspital - University Hospital Bern, University of Bern, Bern, Switzerland.
Nikola KozhuharovDepartment of Cardiology, Inselspital - University Hospital Bern, University of Bern, Bern, Switzerland.
Corinne JuferDepartment of Cardiology, Inselspital - University Hospital Bern, University of Bern, Bern, Switzerland.
Helge ServatiusDepartment of Cardiology, Inselspital - University Hospital Bern, University of Bern, Bern, Switzerland.
Andreas HaeberlinDepartment of Cardiology, Inselspital - University Hospital Bern, University of Bern, Bern, Switzerland.
Fabian NotiDepartment of Cardiology, Inselspital - University Hospital Bern, University of Bern, Bern, Switzerland.
Hildegard TannerDepartment of Cardiology, Inselspital - University Hospital Bern, University of Bern, Bern, Switzerland.
Laurent RotenDepartment of Cardiology, Inselspital - University Hospital Bern, University of Bern, Bern, Switzerland.
Tobias ReichlinDepartment of Cardiology, Inselspital - University Hospital Bern, University of Bern, Bern, Switzerland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Left atrial flutter (LAF) most commonly arises in patients with previous left atrial ablation or surgery. Rarely, it can present as a de novo arrhythmia without previous interventions. Objective: We aimed to compare patient characteristics, pathophysiological mechanisms, and ablation outcomes of patients with de novo LAF with those of patients with postablation LAF. Methods: Patients undergoing LAF ablation between January 2021 and June 2023 were included. Baseline data, arrhythmia mechanisms, and ablation targets were collected. Patients were followed with 7-day Holter electrocardiograms at 3, 6, and 12 months. The primary endpoint was arrhythmia recurrence after a 90-day blanking period. Results: A total of 147 patients with LAF were analyzed (median age 71 years; 65% men). Of those, 32 (22%) presented with de novo LAF, and 115 (78%) presented with postablation LAF. Patients in the de novo group were older (74 years vs 70 years; Conclusion: Patients with de novo LAF are older and leaner than patients with postablation LAF, and the predominant arrhythmia mechanism is anteroseptal localized reentry. Arrhythmia-free survival is similar in both groups.

Indexed as

3D mappingAtrial arrhythmiaElectrophysiologyLeft atrial flutterPulmonary vein isolationPulsed field ablationRadiofrequency ablation

Identifiers

PMID42488141
PMCPMC13390071

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.