Evidence map›Paper›PMID 42488092›Full record

ArticleDiabetology international2026

Characteristics and specificity of diabetic ketoacidosis during Ramadan in pediatrics.

Hend Elber, Selmen Wannes, Gehad Mohamed Gamal, Asma Marzouk, Sarah Ali Saleh, Munther Khalil, Rami Haddad, Manel Ben Fredj, Hisham Momattin

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Article in Diabetology international, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

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9 authors.

Hend ElberDepartment of Pediatrics, Mouwasat Hospital, Imam Al Termithy Street, Uhud, 32263 Dammam, Saudi Arabia.ORCID 0009-0008-9307-5840
Selmen WannesDepartment of Pediatrics, Mouwasat Hospital, Imam Al Termithy Street, Uhud, 32263 Dammam, Saudi Arabia.ORCID 0000-0003-0474-363X
Gehad Mohamed GamalDepartment of Pediatrics, Mouwasat Hospital, Imam Al Termithy Street, Uhud, 32263 Dammam, Saudi Arabia.ORCID 0000-0002-4837-5835
Asma MarzoukDepartment of Pediatrics Ben Arous, Faculty of Medicine of Tunis, Manar University, Tunis, Tunisia.
Sarah Ali SalehDepartment of Pediatrics, Mouwasat Hospital Khobar, Al Khobar, Saudi Arabia.
Munther KhalilDepartment of Pediatrics, Mouwasat Hospital, Imam Al Termithy Street, Uhud, 32263 Dammam, Saudi Arabia.
Rami HaddadDepartment of Pediatrics, Mouwasat Hospital, Imam Al Termithy Street, Uhud, 32263 Dammam, Saudi Arabia.
Manel Ben FredjFaculty of Medicine of Monastir, University of Monastir, 5019 Monastir, Tunisia.ORCID 0000-0001-8529-2660
Hisham MomattinPharmacy Department Mouwasat Medical Service, Al Khobar, Saudi Arabia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Diabetic ketoacidosis remains a significant concern among pediatric patients with diabetes. Ramadan and associated lifestyle changes in pediatric patients (sleeplessness and metabolic stress-intermittent dehydration) should increase the risk of diabetes emergencies. Objective: This study aimed to investigate the specific characteristics of diabetic ketoacidosis (DKA) episodes among pediatric patients with diabetes during the fasting month of Ramadan.Research Design and Methods: A bicentric retrospective analysis was conducted on pediatric patients with DKA admitted to the hospitals (Mouwasat hospital Dammam and khobar,ksa) during a four-year period relative to Ramadan. DKA episodes were categorized as mild, moderate, or severe DKA,and according to corrected electrolyte disturbance in many subcategories (hypernatremic, hyponatremic, or isonatremic DKA and as hypokalemic, normokalemic, or hyperkalemic DKA). A comparative analysis was then performed between two groups defined according to the time of occurrence of DKA during the lunar years: the Ramadan group and the non-Ramadan group. Results: The median age of patients who presented with DKA during Ramadan was [8 (6-11)], with [55%] being male. Among the patients with DKA, 100% had type 1 diabetes mellitus, while [1.7%] had type 2 diabetes mellitus or neonatal diabetes during non-fasting months. The majority of DKA episodes occurred within the first decade of Ramadan [55%]. Variations in demographic factors and electrolyte disturbances among patients with DKA occurring during Ramadan vs. non-Ramadan did not reach statistical significance. The median pH at admission was lower during Ramadan than during non-fasting months ( Conclusions: Diabetic ketoacidosis remains a significant concern among pediatric patients with diabetes during Ramadan. Healthcare providers should emphasize the importance of close monitoring, early detection, and prompt intervention to prevent DKA complications during this religious observance.

Indexed as

AdolescentDiabetic ketoacidosisIntermittent fastingPaediatricsRamadanType 1 diabetes

Identifiers

PMID42488092
PMCPMC13388590

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