ArticlePediatric gastroenterology, hepatology & nutrition2026
Diagnostic Approach to Pediatric Collagenous Gastritis Based on a Case Series and Literature Review.
Article in Pediatric gastroenterology, hepatology & nutrition, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Purpose: Collagenous gastritis (CG) is a rare pediatric disorder characterized by gastrointestinal symptoms and iron-deficiency anemia. Owing to its low prevalence and broad range of nonspecific manifestations, CG is frequently overlooked during diagnosis. This study aimed to propose a diagnostic algorithm for CG and systematically review the published literature. Methods: Four patients aged <18 years diagnosed with CG at a tertiary referral center in Korea between 2003 and 2023 were retrospectively analyzed. In addition, 73 pediatric cases reported worldwide between 1989 and 2024 were reviewed. Results: Among 77 cases, excluding one case without symptom data, 16 patients (20.8%) had no gastrointestinal symptoms other than anemia. Abdominal pain was reported in 37 patients (48.7%), gastrointestinal bleeding in five (6.6%), vomiting in nine (11.8%), and diarrhea in three (3.9%). Anemia was present in 62 patients, and 68 tested negative for Conclusion: CG remains a diagnostically challenging condition that requires a high index of suspicion. Early EGD should be considered in pediatric patients with recurrent gastrointestinal symptoms and treatment-refractory iron-deficiency anemia who test negative for
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