Evidence map›Paper›PMID 42487944›Full record

ArticleFrontiers in medicine2026

Perioperative nutritional support is associated with attenuated early postoperative albumin decline after gastrectomy for gastric cancer: a retrospective cohort study and machine learning prediction model.

Tao Wen, Xikui Zhang, Xiaoping Zhang, Sumei Lv, Liman Yang, Bibo Tan, Feng Xia Liu

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Article in Frontiers in medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

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7 authors.

Tao Wen *Department of Operating Room, The Fourth Hospital of Hebei Medical University, Shijiazhuang, Hebei, China.
Xikui Zhang *Department of Ophthalmology, The Fourth Hospital of Hebei Medical University, Shijiazhuang, Hebei, China.
Xiaoping ZhangDepartment of Operating Room, The Fourth Hospital of Hebei Medical University, Shijiazhuang, Hebei, China.
Sumei LvDepartment of Ophthalmology, The Fourth Hospital of Hebei Medical University, Shijiazhuang, Hebei, China.
Liman YangDepartment of Ophthalmology, The Fourth Hospital of Hebei Medical University, Shijiazhuang, Hebei, China.
Bibo TanDepartment of Gastrointestinal Surgery, The Fourth Hospital of Hebei Medical University, Shijiazhuang, Hebei, China.
Feng Xia LiuDepartment of Nursing, The Fourth Hospital of Hebei Medical University, Shijiazhuang, Hebei, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Perioperative nutritional support is recommended for surgical patients at nutritional risk, but its relationship with early postoperative serum albumin recovery after gastrectomy for gastric cancer remains uncertain, and clinicians lack practical tools to identify patients most likely to show early albumin improvement. Methods: We conducted a retrospective cohort study of 1,529 adults who underwent gastrectomy for gastric cancer at The Fourth Hospital of Hebei Medical University between January and December 2017 and had both preoperative and early postoperative albumin measurements. Perioperative nutritional support was defined using the binary classification available in the source dataset. The primary outcome was postoperative albumin improvement, defined as postoperative albumin exceeding the preoperative value. Secondary outcomes were postoperative total protein improvement and change in albumin (postoperative minus preoperative). Associations were assessed using multivariable linear and logistic regression, and a gradient boosting model using 46 routinely collected preoperative and perioperative variables was developed to predict albumin improvement. Results: Albumin improved in 233 of 1,529 patients (15.2%) and was more common in the nutritional support group than in the no/standard support group (19.2% vs. 12.8%; Discussion: Perioperative nutritional support was associated with an attenuated early postoperative decline in serum albumin after gastrectomy for gastric cancer, and the prediction model showed moderate discrimination for early albumin improvement. External validation and prospective evaluation are needed before clinical deployment.

Indexed as

gastrectomygastric cancermachine learningmalnutritionperioperative nutritional supportprediction modelserum albumin

Identifiers

PMID42487944
PMCPMC13388203

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