ArticleFrontiers in medicine2026
Effect of water intake on routine laboratory test parameters in healthy adults: a cross-sectional study.
Article in Frontiers in medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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8 authors.
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Abstract
Introduction: Fasting before routine blood sampling has been regarded as a standard requirement. However, this practice may cause unnecessary discomfort and lacks sufficient scientific evidence. This study aimed to investigate the effect of water intake on commonly measured complete blood count (CBC) and biochemical parameters. Materials and methods: This two-step study involved two homogeneous cohorts of healthy adult medical postgraduate students. In Step 1, participants from Cohort 1 ( Results: Twelve CBC parameters and 7 biochemical parameters showed statistically significant differences one hour after the intake of 500 mL of water compared with pre-intake values, including leukocytes, lymphocytes, monocytes, erythrocytes, hemoglobin, hematocrit, mean cell volume, mean cell hemoglobin, mean cell hemoglobin concentration, red cell distribution width-standard deviation, platelets, plateletcrit, alkaline phosphatase, total cholesterol, high-density lipoprotein cholesterol, low-density lipoprotein cholesterol, urea, uric acid, and creatinine. The remaining 6 CBC parameters and 5 biochemical parameters showed no statistically significant differences, including neutrophils, eosinophils, basophils, mean platelet volume, platelet distribution width, platelet larger cell ratio, alanine aminotransferase, aspartate aminotransferase, Conclusion: Water intake before routine blood sampling has minimal clinically relevant effects on commonly measured CBC and biochemical parameters in healthy adults.
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