ArticleFrontiers in medicine2026
Harmonic analysis of radial pulse in traditional Chinese medicine: physiological alterations associated with hepatitis B and hepatitis C infections.
Article in Frontiers in medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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1 citing paper in PubMed.
- Radial pulse harmonic analysis for cardiometabolic assessment: a computational and translational mini review.Frontiers in endocrinology · 2026Review
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4 authors.
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Abstract
Background: This study investigated whether harmonic analysis (HA) of radial pressure pulse (RPP) signals, a quantitative approach derived from traditional Chinese pulse diagnosis, is associated with physiological alterations in patients with hepatitis B virus (HBV) and hepatitis C virus (HCV) infections. Methods: A total of 75 participants were enrolled, including 36 healthy controls, 17 patients with HBV infection, and 22 patients with HCV infection. Radial pressure pulse signals were acquired using the Skylark Pulse Analysis System, and harmonic components were calculated from the six radial pulse positions (left and right Cun, Guan, and Chi) following peak alignment and frequency-domain decomposition. Results: Among the harmonic parameters, the first harmonic component (C1) demonstrated significant differences among the three groups (one-way analysis of variance [ANOVA], Conclusion: Alterations in the first harmonic component (C1) of radial pulse waveforms were observed in patients with chronic viral hepatitis, particularly in those with HCV infection. These findings suggest that harmonic analysis may provide complementary information regarding systemic physiological alterations associated with viral hepatitis. However, the exploratory nature of this study, together with the small sample size and modest effect size, warrants cautious interpretation. Larger prospective studies are needed to validate these observations and clarify their clinical significance.
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