Evidence map›Paper›PMID 42487932›Full record

ArticleCase reports in ophthalmology

Case Report: Intravitreal Aflibercept for Refractory Irvine-Gass Syndrome.

Muataz Guma, Jose Vargas, Bader Alqahtani

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Case reports in ophthalmology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Muataz GumaOphthalmology Division, King Abdullah University Hospital, Princess Nourah bint Abdulrahman University, Riyadh, Saudi Arabia.
Jose VargasOphthalmology Division, King Abdullah University Hospital, Princess Nourah bint Abdulrahman University, Riyadh, Saudi Arabia.
Bader AlqahtaniOphthalmology Division, King Abdullah University Hospital, Princess Nourah bint Abdulrahman University, Riyadh, Saudi Arabia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Irvine-Gass syndrome (pseudophakic cystoid macular edema) is a common postoperative complication of cataract surgery. While most cases resolve with topical therapy, refractory cases pose a therapeutic challenge. Case Presentation: A 60-year-old woman developed bilateral cystoid macular edema several weeks after uneventful phacoemulsification. Initial postoperative visual acuity was 20/20 bilaterally, declining to 20/100 despite topical corticosteroids and NSAIDs. Optical coherence tomography confirmed significant intraretinal cystic changes. Intervention: Bilateral intravitreal aflibercept (2.0 mg/0.05 mL) was administered. Outcome: Two weeks post-injection, optical coherence tomography demonstrated complete resolution of edema with restoration of best-corrected visual acuity to 20/20. Conclusion: Intravitreal aflibercept may be an effective treatment option for refractory Irvine-Gass syndrome.

Indexed as

Anti-vascular endothelial growth factorCataract surgeryCystoid macular edemaIrvine-Gass syndromeOptical coherence tomography

Identifiers

PMID42487932
PMCPMC13391060

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.