Evidence map›Paper›PMID 42487922›Full record

ReviewFrontiers in digital health2026

Technological innovation in healthcare: challenges, opportunities and impact on sustainability.

Maria Vallet-Regi, Manuel Doblare, Jose A Garrido, Almudena Fuster-Matanzo, Angel Alberich-Bayarri, María Elena Hernando, Cecilia E García Cena, Marie Destarac Eguizabal, Emilio Bouza

Erratum issuedAbstract readReview
In one paragraph

Review in Frontiers in digital health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors.

Maria Vallet-RegiUniversidad Complutense de Madrid, Madrid, Spain.
Manuel DoblareCentro de Investigación Biomédica en Red en Bioingeniería, Biomateriales y Nanomedicina (CIBER-BBN), Instituto de Salud Carlos III, Madrid, Spain.
Jose A GarridoICREA, Barcelona, Spain.
Almudena Fuster-MatanzoQuibim S.L, Valencia, Spain.
Angel Alberich-BayarriQuibim S.L, Valencia, Spain.
María Elena HernandoInstituto de Investigación Sanitaria Hospital 12 de Octubre, Madrid, Spain.
Cecilia E García CenaUniversidad Politécnica de Madrid, Escuela Técnica Superior de Ingeniería y Diseño Industrial, Madrid, Spain.
Marie Destarac EguizabalOWSD Guatemala, Guatemala, Guatemala.
Emilio BouzaUniversidad Complutense de Madrid, Madrid, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Healthcare technologies are increasingly reshaping how diseases are detected, monitored, treated, and managed across healthcare systems. Advances in artificial intelligence (AI), digital health, remote monitoring, advanced medical devices, and data-driven clinical infrastructures are creating important opportunities to improve prevention, diagnostic accuracy, personalisation of care, workflow efficiency, and long-term healthcare sustainability within the framework of predictive, preventive, personalized, and participatory medicine (4P Medicine). However, despite growing technological sophistication and investment, many innovations fail to achieve scalable and sustainable implementation in real-world clinical environments. This narrative review critically examines the systemic factors that condition the successful translation of healthcare technologies into routine clinical practice, with particular emphasis on the European and Spanish contexts. Rather than focusing exclusively on technological performance, the review analyses the broader regulatory, organisational, financial, ethical, and governance challenges that shape implementation. Key areas discussed include technology transfer, regulatory frameworks, health data governance, and the organisational challenges associated with implementing AI-driven healthcare technologies. The central argument of this review is that the real-world impact of healthcare innovation depends less on technological capability itself than on the capacity of healthcare systems to support validation, regulation, implementation, workforce adaptation, interoperability, and long-term governance. Consequently, the principal challenge for contemporary healthcare systems is no longer simply how to develop new technologies, but how to integrate them safely, equitably, and sustainably into routine clinical practice.

Indexed as

healthcareinnovationpoliciessustainabilitytechnology

Identifiers

PMID42487922
PMCPMC13389938

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.