ArticleLaryngoscope investigative otolaryngology2026
Facial Retaining Ligaments Influence Basal Cell Carcinoma Growth in the Midface and Periorbital Region.
Article in Laryngoscope investigative otolaryngology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Facial Retaining Ligaments Influence Basal Cell Carcinoma Growth in the Midface and Periorbital Region.Laryngoscope investigative otolaryngology · 2026Article
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Authors and funding
5 authors.
Funding
Abstract
Objectives: Facial retaining ligaments (RLs) are well-characterized for their role in soft-tissue support and in rhytidectomy. This study investigates whether RLs also act as anatomical barriers that influence the spread of basal cell carcinoma (BCC). We hypothesized that the dermal insertion of RLs impedes the dermal spread pattern of BCCs, specifically causing them to grow along the RL. Methods: We conducted a retrospective cohort study of 163 patients who underwent Mohs micrographic surgery (MMS) for BCC. Post-MMS defects were used as a proxy for the BCC size and shape. The defects were categorized as "near," "far," or "crossing" based on their proximity to the RL. Defect symmetry was quantified using the perpendicular-to-parallel ratio of the defect relative to the RL. A relative proximity ratio (RPR) was used for continuous linear regression analysis. Results: Analysis revealed significant defect asymmetry in lesions near RLs. The "near" group demonstrated a growth pattern parallel to the RL (ratio of 0.73) compared to the "far" group (ratio of 0.98, Conclusion: RLs correlate with an eccentric, oblong BCC growth pattern parallel to the direction of the ligament. Recognizing lesions within these zones may improve preoperative counseling and reconstructive planning. Level of Evidence: III.
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Registered trials
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