Expression characteristics and prognostic value of mycoplasma pneumoniae DNA, Interleukin-6, and Interleukin-10 levels in children with mycoplasma pneumoniae pneumonia.

Yan Cheng, Juanjuan Wang, Zhiyong Chen

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Article in Pakistan journal of medical sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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3 authors.

Yan ChengYan Cheng, Department of Pediatrics, The Affiliated Hospital 6 of Nantong University, Department of Pediatrics, Yancheng Third People's Hospital, Yancheng, Jiangsu Province 224000, P.R. China.

Juanjuan WangJuanjuan Wang, Department of Pediatrics, The Affiliated Hospital 6 of Nantong University, Department of Pediatrics, Yancheng Third People's Hospital, Yancheng, Jiangsu Province 224000, P.R. China.

Zhiyong ChenZhiyong Chen, Department of Pediatrics, The Affiliated Hospital 6 of Nantong University, Department of Pediatrics, Yancheng Third People's Hospital, Yancheng, Jiangsu Province 224000, P.R. China.

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6 · The paper itself

Abstract

Objectives: To investigate the expression characteristics and prognostic value of Methodology: This was a retrospective analysis of two hundred children who were suspected of having MPP from January 2022 to December 2024 at Yancheng Third People's Hospital. On the basis of the clinical diagnosis and results of the Results: Compared with those in the control group, levels of MP-DNA (t=29.033; p<0.0001), IL-10 (t=18.233; p<0.0001), and IL-6 (t=28.692; p<0.0001) in the study group were greater (P<0.05). MP-DNA (t=27.174; p<0.0001), IL-10 (t=8.400; p<0.0001), and IL-6 (t=8.981; p<0.0001) levels were higher in the poor prognosis group than in the good prognosis group (P<0.05). High levels of MP-DNA, IL-10, and IL-6 are important risk factors for poor prognosis in children with MPP (P<0.05). Compared with individual diagnosis, combined detection of MP-DNA, IL-10, and IL-6 is more effective. Conclusion: Children with MPP have elevated levels of MP-DNA, IL-10, and IL-6, and their high expression is a risk factor for poor prognosis.

Indexed as

Expression characteristicsIL-10IL-6MP-DNAMycoplasma pneumoniae pneumoniaPrognostic value

Identifiers

PMID42487867

DOI10.12669/pjms.42.7.14948

PMCPMC13389905

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