ArticleFrontiers in public health2026
HIV viral suppression outcomes of Tenofovir- and Abacavir-based antiretroviral regimens among children on ART in Zambia.
Article in Frontiers in public health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Introduction: Use of ART has remarkably decreased HIV related morbidity and mortality rates globally. Children living with HIV in Zambia are initiated on an Abacavir-based regimen to suppress viral replication. This study assessed the achievement of HIV viral suppression among children taking Abacavir and Tenofovir-based regimens and the predicting factors associated with viral load suppression in Zambian children. Methods: This was a retrospective cross-sectional analysis of routinely collected data on all children diagnosed with HIV aged below 15 years attending the ART clinic from 1 January 2016 to 31 December 2018 at the Paediatric University Teaching Hospital in Lusaka, Zambia. Logistic regression was used to explore factors associated with HIV virological suppression. Ethical approval for the study was sought from the University of Zambia Biomedical Research Ethical Committee and the National Health Research Authority. Results: About 78.4% of children on ART achieved virological suppression (262/334). An increase in age showed about 20% reduced odds of virological suppression (AOR 0.80, CI 0.71-0.95), while a child on ABC/3TC/LPV-r combination of ART compared to TDF/XTC/DTG, showed about 88% reduced odds of virological suppression (AOR 0.12, CI 0.04-0.41). Conclusion: Despite an increased uptake of ART, the viral suppression found in this study was lower than the UNAIDS target of 95% of people on ART to be virally suppressed. Greater sensitization and education on the importance of treatment adherence are required to achieve this target, and further studies are needed to determine the factors contributing to the low viral load suppression in children.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.