Evidence map›Paper›PMID 42487730›Full record

ArticleSchizophrenia bulletin open2026

Psychosis Risk is Associated with Increased Multimodal Reports of Socially Salient Content in Degraded Stimuli.

Victor Pokorny, Trevor Williams, Danielle Pratt, Joshua Kenney, Lauren M Ellman, Gregory P Strauss, Elaine F Walker, Scott W Woods, Albert R Powers, Philip R Corlett and 6 more

Abstract read
In one paragraph

Article in Schizophrenia bulletin open, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Victor PokornyDepartment of Psychology, Northwestern University, Evanston, IL 60208, United States.ORCID https://orcid.org/0000-0002-1003-0196
Trevor WilliamsDepartment of Psychology, Kent State University, Kent, OH 44240, United States.
Danielle PrattDepartment of Psychology, Northwestern University, Evanston, IL 60208, United States.ORCID https://orcid.org/0000-0003-1581-4317
Joshua KenneyDepartment of Psychiatry, Yale University, New Haven, CT 06519, United States.
Lauren M EllmanDepartment of Psychology & Neuroscience, Temple University, Philadelphia, PA 19122, United States.
Gregory P StraussDepartments of Psychology and Neuroscience, University of Georgia, Athens, GA 30602, United States.
Elaine F WalkerDepartment of Psychology and Program in Neuroscience, Emory University, Atlanta, GA 30322, United States.ORCID https://orcid.org/0000-0002-9798-8101
Scott W WoodsDepartment of Psychiatry, Yale University, New Haven, CT 06519, United States.
Albert R PowersDepartment of Psychiatry, Yale University, New Haven, CT 06519, United States.ORCID https://orcid.org/0000-0003-3057-5043
Philip R CorlettDepartment of Psychiatry, Yale University, New Haven, CT 06519, United States.ORCID https://orcid.org/0000-0002-5368-1992
Judy L ThompsonDepartments of Psychiatry and Neuroscience, University of Rochester Medical Center, Rochester, NY 14642, United States.
Steven M SilversteinDepartments of Psychiatry, Neuroscience and Ophthalmology, University of Rochester Medical Center, Rochester, NY 14642, United States.ORCID https://orcid.org/0000-0002-0699-0960
James A WaltzMaryland Psychiatric Research Center, Department of Psychiatry, University of Maryland School of Medicine, Baltimore, MD 21228, United States.ORCID https://orcid.org/0000-0002-9236-3719
James M GoldMaryland Psychiatric Research Center, Department of Psychiatry, University of Maryland School of Medicine, Baltimore, MD 21228, United States.ORCID https://orcid.org/0000-0002-0109-9554
Jason SchiffmanDepartment of Psychological Science, 4201 Social and Behavioral Sciences Gateway, University of California, Irvine, CA 92697, United States.
Vijay A MittalDepartment of Psychology, Northwestern University, Evanston, IL 60208, United States.ORCID https://orcid.org/0000-0001-9017-5119

Funding

TRAINING PROGRAM IN THE NEUROSCIENCE OF HUMAN COGNITIONT32NS047987 · NINDS · NORTHWESTERN UNIVERSITY AT CHICAGO · PI Rodrigo M Braga, Christina Maria Zelano · 2006 to 2026
$5.6M
2/9 - Predictors and Mechanisms of Conversion to PsychosisU01MH081988 · NIMH · EMORY UNIVERSITY · PI WALKER, ELAINE FRAN · 2008 to 2018
$5.4M
5/5 CAPER: Computerized Assessment of Psychosis RiskR01MH120089 · NIMH · YALE UNIVERSITY · PI CORLETT, PHILIP, WOODS, SCOTT W · 2020 to 2024
$3.1M
Prodromal Inventory for Negative Symptoms (PINS): A Development and Validation StudyR01MH116039 · NIMH · UNIVERSITY OF GEORGIA · PI MITTAL, VIJAY A, STRAUSS, GREGORY P · 2019 to 2023
$3.1M
1/5 CAPER: Computerized Assessment of ProdromE RiskR01MH120090 · NIMH · UNIVERSITY OF MARYLAND BALTIMORE · PI GOLD, JAMES M. · 2020 to 2024
$2.9M
4/5 CAPER: Computerized assessment of psychosis riskR01MH120092 · NIMH · UNIVERSITY OF GEORGIA · PI STRAUSS, GREGORY P · 2020 to 2024
$2.0M
2/5 CAPER Computerized assessment of psychosis riskR01MH120088 · NIMH · NORTHWESTERN UNIVERSITY · PI MITTAL, VIJAY A · 2020 to 2024
$2.0M
1/3-Community Psychosis Risk Screening: An Instrument Development Study SupplementR01MH112613 · NIMH · TEMPLE UNIV OF THE COMMONWEALTH · PI ELLMAN, LAUREN M · 2017 to 2022
$1.8M
CAPER: Computerized Assessment of Psychosis Risk SupplementR01MH120091 · NIMH · TEMPLE UNIV OF THE COMMONWEALTH · PI ELLMAN, LAUREN M · 2020 to 2024
$1.6M
Administrative Supplement - 3/3: Community Psychology Risk Screening: An Instrument Development StudyR01MH112612 · NIMH · UNIVERSITY OF MARYLAND BALTIMORE COUNTY · PI PITTS, STEVEN C, SCHIFFMAN, JASON E · 2017 to 2022
$1.3M
2/3 Community psychosis risk screening: An instrument development studyR01MH112545 · NIMH · NORTHWESTERN UNIVERSITY · PI MITTAL, VIJAY A · 2017 to 2021
$1.2M
Mechanisms Underlying Emotion Regulation Abnormalities in Youth at Clinical High-Risk for PsychosisR21MH119438 · NIMH · UNIVERSITY OF GEORGIA · PI STRAUSS, GREGORY P · 2019 to 2020
$415k
NIMH NIH HHS R01 MH112545NIMH NIH HHS R01 MH112612NIMH NIH HHS R01 MH112613NIMH NIH HHS R01 MH116039NIMH NIH HHS R01 MH120088NIMH NIH HHS R01 MH120089NIMH NIH HHS R01 MH120090NIMH NIH HHS R01 MH120091NIMH NIH HHS R01 MH120092NIMH NIH HHS R21 MH119438NIMH NIH HHS U01 MH081988NINDS NIH HHS T32 NS047987
6 · The paper itself

Abstract

Background and Hypothesis: Humans are capable of detecting faces and speech in noisy environments. While such detection is generally adaptive, we hypothesize that hallucinations and perceptual distortions arise from overdetection of such features under uncertainty. Study Design: To test this hypothesis, we measured face and speech detection rates in over 800 adolescents and young adults, oversampled for individuals at risk of developing psychotic disorders. Study Results: Individuals who reported seeing more faces in degraded 2-tone images tended to report hearing more speech in degraded filtered audio clips ( Conclusions: Our results suggest that a supramodal tendency to report the presence of socially salient content under uncertainty may contribute to positive perceptual symptoms and index clinical risk for psychosis. We place these findings within the broader literature and discuss the potential utility of these highly scalable behavioral measures for better identifying individuals at risk for developing psychosis.

Indexed as

Bayesian inferenceclinical high-riskhallucinationsperceptionperceptual priorspredictive coding

Identifiers

PMID42487730
PMCPMC13390576

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.