Evidence map›Paper›PMID 42487663›Full record

ArticleImmunometabolism (Cobham, Surrey)2026

Lipid-driven epigenetic exhaustion: linking palmitate metabolism to CD8

Desh Raj, Mahesh Kathania, Tuoqi Wu, Arianne L Theiss, K Venuprasad

Abstract read
In one paragraph

Article in Immunometabolism (Cobham, Surrey), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Desh RajDepartment of Internal Medicine, UT Southwestern Medical Center, Dallas, TX, USA.
Mahesh KathaniaDepartment of Internal Medicine, UT Southwestern Medical Center, Dallas, TX, USA.
Tuoqi WuDepartment of Immunology, UT Southwestern Medical Center, Dallas, TX, USA.
Arianne L TheissDivision of Gastroenterology and Hepatology, Department of Medicine, University of Colorado School of Medicine, Aurora, CO, USA.
K VenuprasadDepartment of Internal Medicine, UT Southwestern Medical Center, Dallas, TX, USA.

Funding

Regulation of CD8+T cells by Zbtb42R01CA266072 · NCI · UT SOUTHWESTERN MEDICAL CENTER · PI Venuprasad K Poojary · 2022 to 2026
$2.1M
Znf740 in the regulation of CD8+T cell exhaustionR01CA282143 · NCI · UT SOUTHWESTERN MEDICAL CENTER · PI Venuprasad K Poojary · 2023 to 2026
$2.1M
Regulation of Zbtb44-Eomes complex in CD8+T cells and anti-tumor immunityR01AI155786 · NIAID · UT SOUTHWESTERN MEDICAL CENTER · PI POOJARY, VENUPRASAD K · 2021 to 2025
$2.1M
NCI NIH HHS R01 CA266072NCI NIH HHS R01 CA282143NIAID NIH HHS R01 AI155786
6 · The paper itself

Abstract

In a recent study published in

Indexed as

acetyl CoAcytotoxic T cellspalmitateT-cell exhaustion

Identifiers

PMID42487663
PMCPMC13390978

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.