Evidence map›Paper›PMID 42487514›Full record

ArticleJournal of pediatric gastroenterology and nutrition2026

The impacts of energy and protein provision on anthropometric changes in infants with critical congenital heart disease.

Colin R Tang-Whitmore, Cydney Coleman, Brittany Faanes, Laura Gearman, Brian F Joy, Stacie Knutson, Benjamin W Langworthy, Katie M Pfister, Catherine Larson-Nath

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Article in Journal of pediatric gastroenterology and nutrition, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Colin R Tang-WhitmoreDepartment of Pediatrics, University of Minnesota, Minneapolis, Minnesota, USA.ORCID https://orcid.org/0009-0006-9307-5168
Cydney ColemanDepartment of Pediatrics, University of Minnesota, Minneapolis, Minnesota, USA.
Brittany FaanesDepartment of Pediatrics, University of Minnesota, Minneapolis, Minnesota, USA.
Laura GearmanDepartment of Nutrition, MHealth Fairview Masonic Children's Hospital, Minneapolis, Minnesota, USA.
Brian F JoyDepartment of Pediatrics, University of Minnesota, Minneapolis, Minnesota, USA.
Stacie KnutsonDepartment of Pediatrics, University of Minnesota, Minneapolis, Minnesota, USA.
Benjamin W LangworthyDepartment of Biostatistics and Health Data Science, University of Minnesota, Minneapolis, Minnesota, USA.
Katie M PfisterDepartment of Pediatrics, University of Minnesota, Minneapolis, Minnesota, USA.
Catherine Larson-NathDepartment of Pediatrics, University of Minnesota, Minneapolis, Minnesota, USA.ORCID https://orcid.org/0000-0001-8797-2651

Funding

None
6 · The paper itself

Abstract

objectivesMalnutrition in patients with critical congenital heart disease (CCHD) is associated with worse outcomes, however, feeding challenges, and changes in metabolic demands obscure the relationship between nutrient intake and growth in this patient population. We examined the relationship between nutrition provision (caloric and protein intake) and anthropometric indices (weight-for-age z-score [WAZ], length-for-age z-score [LAZ], and occipital-frontal-circumference-for-age [OAZ]).

methodsA single-center prospective cohort study of infants admitted to cardiac intensive care at a tertiary care children's hospital with CCHD between January 2020 and August 2023. Changes in weekly anthropometric measures were modeled with weekly protein and energy intake using a generalized estimating equation model, controlling for relevant factors. The effects of meeting protein (at least 2 g/kg/day) and energy (at least 120 kcal/kg/day) goals on anthropometric z-scores were also assessed, with a significance threshold of p < 0.05 and no corrections for multiple comparisons.

resultsThirty-six patients were enrolled (18 male), including eight with single ventricle and 28 with biventricular physiology. Increased energy and protein intake were associated with greater expected improvements in growth parameters. Among patients who met the daily caloric goal of at least 120 kcal/kg, there was a significant increase in change in LAZ. Meeting the protein goal of at least 2 g/kg was not associated with changes in WAZ, LAZ, and OAZ.

conclusionIncreased energy and protein provision is associated with greater change in all anthropometric indices in neonates with CCHD demonstrating the importance of nutrition provision in this population.

Indexed as

Body HeightBody WeightDietary ProteinsEnergy IntakeHeart Defects, CongenitalAnthropometryCritical IllnessFemaleHumansInfant, NewbornInfant Nutrition DisordersMaleNutritional StatusProspective StudiesDietary Proteinsanthropometricscritical illnessenteral nutritiongrowthpediatric cardiology

Identifiers

PMID42487514
PMCPMC13646035

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.