Evidence map›Paper›PMID 42487485›Full record

ArticleClinical and translational medicine2026

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Ze-Yu Lu, Peng-Bo Chen, Qing-Yin Xu, Muradil Mardan, Yue-Hua Yang, Tao Liu, Wen-Ning Xu, Huo-Liang Zheng, Hao Cai, Hui Deng and 5 more

Abstract read
In one paragraph

Article in Clinical and translational medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Ze-Yu LuSpine Center, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.ORCID 0000-0002-3051-9183
Peng-Bo ChenSpine Center, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.ORCID 0000-0003-1783-3773
Qing-Yin XuSpine Center, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.ORCID 0000-0002-3579-5910
Muradil MardanSpine Center, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.ORCID 0009-0000-9315-177X
Yue-Hua YangDepartment of Orthopedic Surgery, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Tao LiuDepartment of Orthopedic Surgery, The Affiliated People's Hospital of Jiangsu University, Zhenjiang, China.ORCID 0000-0002-1482-4858
Wen-Ning XuDepartment of Spinal Surgery, Orthopedic Medical Center, Zhujiang Hospital, Southern Medical University, Guangzhou, China.ORCID 0000-0002-4520-3827
Huo-Liang ZhengSpine Center, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.ORCID 0000-0002-0523-6798
Hao CaiSpine Center, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Hui DengSpine Center, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.ORCID 0009-0000-5452-7623
Xing-Xu HuangSchool of Life Science and Technology, ShanghaiTech University, Shanghai, China.ORCID 0000-0001-8934-1247
Bo LiSpine Center, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.ORCID 0000-0002-0292-4691
Sheng-Dan JiangSpine Center, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.ORCID 0000-0001-6653-1881
Lei-Sheng JiangSpine Center, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.ORCID 0000-0001-6503-7443
Xin-Feng ZhengSpine Center, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.ORCID 0000-0001-8355-2967

Funding

National Natural Science Foundation of China 81772374National Natural Science Foundation of China 82172474Shanghai Municipal Health Commission 20234Y0037
6 · The paper itself

Abstract

Bone health is critically dependent on the precise regulation of bone-forming cells, which are significantly impacted by glucocorticoids. Although DNA damage-regulated autophagy modulator 1 (DRAM1) plays a key role in autophagy, its involvement in glucocorticoid-induced osteoporosis has not been fully explored. Here, we showed that alterations in N

Indexed as

AdenosineAutophagyDexamethasoneMembrane ProteinsOsteogenesisRNA-Binding ProteinsAnimalsCell DifferentiationGlucocorticoidsHumansMesenchymal Stem CellsMiceMice, KnockoutAdenosineDexamethasoneGlucocorticoidsMembrane ProteinsN-methyladenosineRNA-Binding ProteinsYthdf1 protein, mouseautophagydexamethasoneN6‐methyladenosineosteogenic differentiationWnt/β‐catenin signalling

Identifiers

PMID42487485
PMCPMC13392500

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.