ArticleLuminescence : the journal of biological and chemical luminescence2026
Revealing the Dualistic Toxicity of 1,4-Naphthoquinone in Earthworms: Cytotoxic Damage in Coelomocytes and Spectroscopic Insights Into Catalase Activation.
Article in Luminescence : the journal of biological and chemical luminescence, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
1,4-Naphthoquinone (1,4-NQ) is an important organic chemical intermediate and a byproduct of polycyclic aromatic hydrocarbons degradation, harmful to soil organisms like earthworms. The underlying toxic mechanisms in earthworms remain unclear, but research highlights coelomocytes and catalase (CAT) as crucial for studying its cytotoxic and proteotoxic effects. 1,4-NQ caused cell membrane damage, mitochondrial injury, and oxidative stress. Studies using spectroscopy, isothermal titration calorimetry, and molecular simulation revealed that 1,4-NQ increased cell membrane permeability, indicated by higher LDH release and decreased Na
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