Evidence map›Paper›PMID 42487135›Full record

ArticleTranslational neurodegeneration2026

Functional analysis of late-onset Alzheimer's disease risk genes in Caenorhabditis elegans identifies regulators of neuronal aging.

Swapnil G Waghmare, Meera M Krishna, Emily C Maccoux, Ariel L Franitza, Brian A Link, Lezi E

Abstract readLetter
In one paragraph

Article in Translational neurodegeneration, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. [Bushen Yijing Formula attenuates amyloid β-protein deposi-tion and oxidative damage inZhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences · 2026
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Swapnil G WaghmareDepartment of Cell Biology, Neurobiology and Anatomy, Medical College of Wisconsin, 8701 W Watertown Plank Road, Milwaukee, WI, 53226, USA.
Meera M KrishnaDepartment of Cell Biology, Neurobiology and Anatomy, Medical College of Wisconsin, 8701 W Watertown Plank Road, Milwaukee, WI, 53226, USA.
Emily C MaccouxNeuroscience Research Center, Medical College of Wisconsin, 8701 W Watertown Plank Road, Milwaukee, WI, 53226, USA.
Ariel L FranitzaNeuroscience Research Center, Medical College of Wisconsin, 8701 W Watertown Plank Road, Milwaukee, WI, 53226, USA.
Brian A LinkDepartment of Cell Biology, Neurobiology and Anatomy, Medical College of Wisconsin, 8701 W Watertown Plank Road, Milwaukee, WI, 53226, USA.
Lezi EDepartment of Cell Biology, Neurobiology and Anatomy, Medical College of Wisconsin, 8701 W Watertown Plank Road, Milwaukee, WI, 53226, USA. lezie@mcw.edu.

Funding

Enhancing and expanding the CGC Strain CollectionP40OD010440 · OD · UNIVERSITY OF MINNESOTA · PI Aric L Daul, Ann E. Rougvie · 2012 to 2026
$7.5M
Functional Analysis of Late-onset Alzheimer’s Disease-Associated Genes in Neurodegeneration and Protein Aggregation-induced NeurotoxicityR03AG087390 · NIA · MEDICAL COLLEGE OF WISCONSIN · PI E, LEZI · 2025 to 2025
$312k
Advancing a Healthier Wisconsin Endowment 5520482Advancing a Healthier Wisconsin Endowment 5520760NIA NIH HHS R03 AG087390NIH HHS AG087390NIH HHS P40 OD010440
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Identifiers

PMID42487135
PMCPMC13393840

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.