Evidence map›Paper›PMID 42486952›Full record

ArticleArchives of osteoporosis2026

The osteoporosis care cascade in postmenopausal women with and without cardiovascular disease: a nationally representative cross-sectional study using dual-energy X-ray absorptiometry.

Deuk Hee Choi, Je Il Ryu

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Article in Archives of osteoporosis, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

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2 authors.

Deuk Hee ChoiGraduate School, College of Business, Hanyang University, Seoul, Republic of Korea.
Je Il RyuGraduate School, College of Business, Hanyang University, Seoul, Republic of Korea. ryujeil@hanyang.ac.kr.

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6 · The paper itself

Abstract

No study has used measured bone mineral density (BMD) data to compare osteoporosis care gaps between women with and without cardiovascular disease. Among 5,420 postmenopausal women with dual-energy X-ray absorptiometry (DXA), 71.1% with osteoporosis were undiagnosed and 87.2% untreated; cardiovascular disease history did not narrow these care gaps. PURPOSE: No population-based study has used measured bone mineral density (BMD) data to compare the osteoporosis care cascade between women with and without cardiovascular disease (CVD). This study quantified the dual-energy X-ray absorptiometry (DXA)-based care cascade in South Korean postmenopausal women and tested whether CVD history is associated with care gaps.

methodsData were from the Korea National Health and Nutrition Examination Survey (KNHANES) 2008-2011 (n = 5,420 women aged ≥50 years with valid DXA). Osteoporosis was defined as a minimum T-score ≤ -2.5. CVD was defined as self-reported physician-diagnosed stroke, myocardial infarction, or angina pectoris. Multivariable logistic regression identified predictors of unawareness and non-treatment.

resultsOf 5,420 women, 1,957 had DXA-confirmed osteoporosis (weighted prevalence, 34.0%); weighted awareness was 28.9% and treatment 12.8%. Awareness (35.7% vs. 28.4%, p = 0.084) and treatment (16.5% vs. 12.6%, p = 0.238) did not differ between CVD and non-CVD groups. After adjustment, CVD history was not associated with unawareness (odds ratio [OR] 0.76; 95% confidence interval [CI] 0.51-1.12; p = 0.162) or non-treatment (OR 0.79; 95% CI 0.46-1.37; p = 0.403). Dyslipidemia was independently linked to lower odds of both unawareness and non-treatment.

conclusionIn this cohort, 71.1% of women with T-score ≤ -2.5 had no prior physician diagnosis of osteoporosis, and only 12.8% were on medication. The CVD and non-CVD groups did not differ in awareness or treatment rates, suggesting that cardiovascular follow-up does not facilitate osteoporosis detection.

Indexed as

Cardiovascular DiseasesOsteoporosis, PostmenopausalAbsorptiometry, PhotonAgedBone DensityCross-Sectional StudiesFemaleHumansMiddle AgedNutrition SurveysPrevalenceRepublic of KoreaAwarenessBone densityCardiovascular diseasesCare cascadeOsteoporosisTreatment gap

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.