"The feasibility of free septal mucosal grafts in preventing postoperative middle meatus synechia after endoscopic sinus surgery".

Ahmed Elgendy, Saad Elzayat, Ali Gamal El-Ouny, Ahmed Morshedy, Sobhy Khaled, Ibrahim Gehad

Abstract readObservational Study

In one paragraph

Observational study in Scientific reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

Authors and funding

6 authors.

Ahmed ElgendyOtolaryngology Department, Kafrelsheikh University hospital, El-giesh street, Kafrelsheikh, 33155, Egypt.

Saad ElzayatOtolaryngology Department, Kafrelsheikh University hospital, El-giesh street, Kafrelsheikh, 33155, Egypt.

Ali Gamal El-OunyOtolaryngology Department, Kafrelsheikh University hospital, El-giesh street, Kafrelsheikh, 33155, Egypt.

Ahmed MorshedyOtolaryngology Department, Kafrelsheikh University hospital, El-giesh street, Kafrelsheikh, 33155, Egypt.

Sobhy KhaledOtolaryngology Department, Kafrelsheikh University hospital, El-giesh street, Kafrelsheikh, 33155, Egypt.

Ibrahim GehadOtolaryngology Department, Kafrelsheikh University hospital, El-giesh street, Kafrelsheikh, 33155, Egypt. Ibrahimgehad94@gmail.com.ORCID 0009-0009-4993-3083

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study aimed to evaluate the feasibility and safety of using a free septal mucosal graft to prevent middle meatal synechiae following endoscopic sinus surgery (ESS). This prospective observational study was conducted at a tertiary referral center between March 2022 and February 2024. Adult patients with chronic rhinosinusitis without nasal polyps (CRSsNP) who were refractory to medical therapy were included. All patients underwent unilateral ESS followed by placement of a free septal mucosal graft over exposed bone in the middle meatus. Postoperative outcomes were assessed using the Sinonasal Outcome Test-22 (SNOT-22), Lund-Kennedy Endoscopic Score (LKES), and Perioperative Sinus Endoscopy (POSE) score. A total of 116 patients completed the study. Significant improvement in SNOT-22 scores was observed at 6 months postoperatively (p < 0.001). Significant improvement was also noted in endoscopic findings (LKES, p < 0.001). Stable middle turbinate position without lateralization was achieved in 91 (78%) of cases. Free septal mucosal grafting appears to be a feasible, biocompatible, and technically straightforward method to reduce middle meatal synechiae following ESS.

Indexed as

EndoscopyNasal MucosaParanasal SinusesPostoperative ComplicationsRhinosinusitisAdultChronic DiseaseFeasibility StudiesFemaleHumansMaleMiddle AgedProspective StudiesSinusitisTissue AdhesionsTreatment OutcomeChronic rhinosinusitisEndoscopic sinus surgeryFree septal mucosal graftMiddle meatal synechiae preventionMiddle turbinate lateralization

Identifiers

PMID42486914

DOI10.1038/s41598-026-63253-0

PMCPMC13392350

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