Evidence map›Paper›PMID 42486913›Full record

ArticleActa neuropathologica2026

Validation of proposed cIMPACT-NOW update 12 molecular grading criteria for IDH-mutant astrocytoma.

Timothy E Richardson, Jorge Samanamud, Michael Christian Virata, Ema Mir, Shrishtee Kandoi, Cheyanne C Slocum, Diana D Shi, Milan R Savani, Raquel T Yokoda, Sachein Sharma and 19 more

Abstract readLetter
PubMed Full text at PMC Publisher
In one paragraph

Article in Acta neuropathologica, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

29 authors.

Timothy E RichardsonDepartment of Pathology, Molecular and Cell-Based Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA. timothy.richardson@mountsinai.org.
Jorge SamanamudDepartment of Pathology, Molecular and Cell-Based Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.
Michael Christian VirataDepartment of Pathology, Molecular and Cell-Based Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.
Ema MirDepartment of Pathology, Molecular and Cell-Based Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.
Shrishtee KandoiDepartment of Pathology, Molecular and Cell-Based Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.
Cheyanne C SlocumDepartment of Pathology, Molecular and Cell-Based Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.
Diana D ShiChildren's Medical Center Research Institute, University of Texas Southwestern Medical Center, Dallas, TX, 75390, USA.
Milan R SavaniChildren's Medical Center Research Institute, University of Texas Southwestern Medical Center, Dallas, TX, 75390, USA.
Raquel T YokodaDepartment of Laboratory Medicine and Pathology, Mayo Clinic, Phoenix, AZ, 85054, USA.
Sachein SharmaCaris Life Sciences, Irving, TX, 75039, USA.
Raymund L YongDepartment of Neurosurgery, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.
Joshua B BedersonDepartment of Neurosurgery, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.
Thenzing J Silva-HurtadoDepartment of Pathology, Molecular and Cell-Based Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.
Phuong NguyenDepartment of Pathology, Molecular and Cell-Based Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.
Satomi HiyaDepartment of Pathology, Molecular and Cell-Based Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.
Carolina Maldonado-DíazDepartment of Pathology, Molecular and Cell-Based Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.
Kevin ClareDepartment of Pathology, Molecular and Cell-Based Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.
Meenakshi VijDepartment of Pathology, Molecular and Cell-Based Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.
Yurika NishikawaDepartment of Pathology, Molecular and Cell-Based Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.
Melissa UmphlettDepartment of Pathology, Molecular and Cell-Based Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.
Kimmo J HatanpaaDepartment of Pathology, University of Texas Southwestern Medical Center, Dallas, TX, 75390, USA.
Steven BremDepartment of Neurosurgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA.
Mariano S ViapianoDepartment of Neurosurgery, State University of New York, Upstate Medical University, Syracuse, NY, 13210, USA.
Matija SnuderlDepartment of Pathology, New York University Langone Health, New York, NY, 10016, USA.
Dolores HambardzumyanDepartment of Neurosurgery, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.
Jamie M WalkerDepartment of Pathology, Molecular and Cell-Based Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.
Kalil G AbdullahDepartment of Neurosurgery, University of Pittsburgh School of Medicine, 200 Lothrop St, Pittsburgh, PA, 15213, USA.
Samuel K McBrayerChildren's Medical Center Research Institute, University of Texas Southwestern Medical Center, Dallas, TX, 75390, USA.
Nadejda M TsankovaDepartment of Pathology, Molecular and Cell-Based Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AstrocytomaCCND2CDK4CDKN2A/BDiffuse gliomaEGFRGlioblastomaMethylation profilingMolecular grading featuresOligodendrogliomaPrognosis

Identifiers

PMID42486913
PMCPMC13391642

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.