Evidence map›Paper›PMID 42486670›Full record

ArticleeNeuro2026

Production of Mouse Ultrasonic Vocalizations and Distress Calls Is Associated with Different Patterns of Fos Expression in the Nucleus Retroambiguus.

Patryk Ziobro, Da-Jiang Zheng, Aditya Rawal, Zizhan Zhou, Asmita Mittal, Katherine A Tschida

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in eNeuro, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Patryk ZiobroDepartment of Psychology, Cornell University, Ithaca, New York 14853.
Da-Jiang ZhengDepartment of Psychology, Cornell University, Ithaca, New York 14853.ORCID https://orcid.org/0000-0002-0081-8385
Aditya RawalDepartment of Psychology, Cornell University, Ithaca, New York 14853.
Zizhan ZhouDepartment of Psychology, Cornell University, Ithaca, New York 14853.
Asmita MittalDepartment of Psychology, Cornell University, Ithaca, New York 14853.
Katherine A TschidaDepartment of Psychology, Cornell University, Ithaca, New York 14853 kat227@cornell.edu.ORCID https://orcid.org/0000-0002-8171-1722

Funding

Neural Circuits for Context-Dependent Control of Vocal CommunicationR01MH136887 · NIMH · CORNELL UNIVERSITY · PI Katherine Tschida · 2024 to 2026
$1.2M
NIMH NIH HHS R01 MH136887
6 · The paper itself

Abstract

Animals produce different vocalization types, which differ in their acoustic features and are produced in different behavioral contexts. How vocalization-related brain circuits are organized to enable the production of different vocalization types remains poorly understood. The nucleus retroambiguus (RAm) is a hindbrain premotor region that regulates the production of both ultrasonic vocalizations (USVs) and distress calls (squeaks) in adult mice, but whether distinct or overlapping populations of RAm neurons are recruited during the production of these two vocalization types is unknown. In the current study, we used Fos immunohistochemistry to compare the counts and spatial distributions of Fos-positive RAm neurons in males and females that produced USVs and females that produced courtship squeaks. We also combined in vivo activity-dependent (TRAP2) labeling with Fos immunohistochemistry to directly compare Fos expression associated with the production of USVs and courtship squeaks in the same females. Our findings suggest that RAm contains three vocalization-related populations of neurons: squeak-related neurons, USV-related neurons, and shared neurons that are recruited during both vocalization types. These findings refine current models of the premotor control of vocalization and set the stage for future work to explore anatomical and functional heterogeneity within RAm.

Indexed as

NeuronsProto-Oncogene Proteins c-fosVocalization, AnimalAnimalsCourtshipFemaleMaleMice, Inbred C57BLUltrasonicsFos protein, mouseProto-Oncogene Proteins c-fosFosmousenucleus retroambiguuspremotorsqueakultrasonic vocalization

Identifiers

PMID42486670
PMCPMC13484922

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.