Evidence map›Paper›PMID 42486637›Full record

ArticleJournal of the American Chemical Society2026

Excited-State Intramolecular Proton Transfer Enables Self-Reporting Fluorescent Photoaffinity Labeling in Live Cells.

Kostiantyn Kozoriz, Dhiraj P Murale, Seong Cheol Hong, Kyung Tae Hong, Md Mamunul Haque, Yun Kyung Kim, Jun-Seok Lee

Abstract read
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Article in Journal of the American Chemical Society, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Kostiantyn KozorizDepartment of Chemistry & School of Transdisciplinary Innovations, Seoul National University, Gwanak Ro-1, Gwanak gu, Seoul 08826, Republic of Korea.ORCID 0000-0003-1915-6307
Dhiraj P MuraleBiomedical Research Division & Brain Science Institute, Korea Institute of Science and Technology, Hwarangro 14gil 5, Seungbuk-gu, Seoul 02792, Republic of Korea.
Seong Cheol HongBiomedical Research Division & Brain Science Institute, Korea Institute of Science and Technology, Hwarangro 14gil 5, Seungbuk-gu, Seoul 02792, Republic of Korea.
Kyung Tae HongDepartment of Chemistry & School of Transdisciplinary Innovations, Seoul National University, Gwanak Ro-1, Gwanak gu, Seoul 08826, Republic of Korea.
Md Mamunul HaqueBiomedical Research Division & Brain Science Institute, Korea Institute of Science and Technology, Hwarangro 14gil 5, Seungbuk-gu, Seoul 02792, Republic of Korea.ORCID 0000-0002-3494-4953
Yun Kyung KimBiomedical Research Division & Brain Science Institute, Korea Institute of Science and Technology, Hwarangro 14gil 5, Seungbuk-gu, Seoul 02792, Republic of Korea.ORCID 0000-0002-8682-120X
Jun-Seok LeeDepartment of Chemistry & School of Transdisciplinary Innovations, Seoul National University, Gwanak Ro-1, Gwanak gu, Seoul 08826, Republic of Korea.ORCID 0000-0003-3641-1728

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Photoaffinity labeling (PAL) has long served as the central strategy for capturing transient biomolecular interactions in living cells. However, conventional photo-cross-linking tags rely on highly reactive intermediates that react indiscriminately with solvents and generate heterogeneous cross-linked products. Here, we report an excited-state intramolecular proton transfer (ESIPT) chemistry that addresses these limitations within a single scaffold. Upon photoactivation, 2-(2'-hydroxyphenyl)benzimidazole (

Identifiers

PMID42486637

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.