Evidence map›Paper›PMID 42485656›Full record

Trial reportPhysiotherapy research international : the journal for researchers and clinicians in physical therapy2026

Effectiveness of Sensorimotor and Balance Training Compared to Conventional Physiotherapy on Balance and Quality of Life in Chemotherapy-Induced Peripheral Neuropathy: A Randomised Controlled Trial.

Anisha R Pednekar, Sachin Gawande, Alisha Gracias

Abstract readRandomized Controlled TrialComparative Study
In one paragraph

Trial report in Physiotherapy research international : the journal for researchers and clinicians in physical therapy, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Anisha R PednekarDepartment of Orthopaedic Surgery, Allied Health Science (Physiotherapy Course), Goa Medical College, Bambolim, Goa, India.ORCID https://orcid.org/0009-0001-2283-2743
Sachin GawandeDepartment of Orthopaedic Surgery, Allied Health Science (Physiotherapy Course), Goa Medical College, Bambolim, Goa, India.ORCID https://orcid.org/0000-0003-0657-8578
Alisha GraciasDepartment of Orthopaedic Surgery, Allied Health Science (Physiotherapy Course), Goa Medical College, Bambolim, Goa, India.ORCID https://orcid.org/0000-0002-9545-558X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundChemotherapy-induced peripheral neuropathy (CIPN) is a debilitating side effect that leads to sensory deficits, impaired balance, and a reduced quality of life (QoL). This study evaluates the effectiveness of sensorimotor and balance training compared with conventional physiotherapy.

objectiveDetermine whether integrating sensorimotor and balance training results in greater improvements in balance, neuropathic symptoms, and QoL among patients with CIPN.

methodsA single-blinded randomised controlled trial was conducted with 86 participants undergoing neurotoxic chemotherapy. Outcomes, measured at baseline, Week 4, and follow-up at Week 6, included the Michigan Neuropathy Screening Instrument (MNSI), Berg Balance Scale (BBS), and Functional Assessment of Cancer Therapy-General (FACT-G).

resultsLinear mixed-effects modelling revealed significant group × time interactions for balance, physical well-being, emotional well-being, and functional well-being, favouring the experimental group (all p < 0.001). Large effect sizes were observed for balance (d = 0.70-0.82), physical well-being (d = 0.76-0.80), and functional well-being (d = 0.56-0.75). Social well-being showed a small, transient improvement at Week 4 (d = 0.32) that was not sustained at Week 6.

conclusionsSensorimotor and balance training significantly enhance balance, reduce neuropathic symptoms, and improve QoL in patients with CIPN.

Indexed as

Antineoplastic AgentsExercise TherapyPeripheral Nervous System DiseasesPhysical Therapy ModalitiesPostural BalanceQuality of LifeAdultAgedFemaleHumansMaleMiddle AgedSingle-Blind MethodTreatment OutcomeAntineoplastic Agentsbalance trainingchemotherapy‐induced peripheral neuropathyphysiotherapyquality of lifesensorimotor training

Identifiers

PMID42485656
PMCPMC13391165

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.