Evidence map›Paper›PMID 42485565›Full record

ReviewPlant, cell & environment2026

Harnessing Natural Diversity and Rational Design for Enhanced Plant Immunity.

Nathan Diplock, Jennifer D Lewis

Abstract readReview
In one paragraph

Review in Plant, cell & environment, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Nathan DiplockDepartment of Plant and Microbial Biology, University of California Berkeley, Berkeley, California, USA.ORCID https://orcid.org/0000-0002-4208-0892
Jennifer D LewisDepartment of Plant and Microbial Biology, University of California Berkeley, Berkeley, California, USA.ORCID https://orcid.org/0000-0003-4337-8292

Funding

Agricultural Research Service 2030-12210-003-000DGraduate Research Fellowship ProgramNational Science Foundation IOS-1557661U.S. Department of Agriculture 2024-06679
6 · The paper itself

Abstract

Plant pathogens cause crop loss. Genetic resistance, through natural genetic diversity or engineered resistance, can be highly effective in protecting plants from infection. Genetic resistance from wild relatives of crops has been successfully introduced into crops to control pathogen infection. Natural genetic diversity has also been used to dissect the molecular mechanisms of immunity. Pathogen recognition can be engineered due to advances in structural and computational biology, which have accelerated rational design approaches. We specifically focus on natural and engineered diversity in indirect recognition of pathogens, where the pathogen modifies a host protein and the modification is detected by a plant immune receptor, as these recognition systems are particularly common in bacterial pathogen resistance. We explore natural genetic diversity for indirect recognition at three scales (1) across species (2) within species and (3) within individuals. Finally, we extend these insights to approaches for rational engineering of plant-pathogen recognition.

Indexed as

Genetic VariationPlant DiseasesPlant ImmunityPlantsDisease ResistanceHost-Pathogen Interactionsdecoydisease resistanceengineeringguardeenatural diversityNLRplant immunity

Identifiers

PMID42485565
PMCPMC13646672

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.