Evidence map›Paper›PMID 42485509›Full record

Trial reportRevista da Escola de Enfermagem da U S P2026

The effect of Bach flower remedies on hope and quality of life in people with advanced cancer: a triple-blind randomized clinical trial.

Leonel Dos Santos Silva, Amanda Gomes de Miranda, Larissa Marcondes, Ruth Natalia Teresa Turrini, Paulo Ricardo Bittencourt Guimarães, Maria de Fátima Mantovani, Luciana de Alcantara Nogueira, Luciana Puchalski Kalinke

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Revista da Escola de Enfermagem da U S P, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Leonel Dos Santos SilvaUniversidade Federal do Paraná, Programa de Pós-Graduação em Enfermagem, Curitiba, PR, Brazil.ORCID http://orcid.org/0000-0002-8359-5622
Amanda Gomes de MirandaUniversidade Federal do Paraná, Programa de Pós-Graduação em Enfermagem, Curitiba, PR, Brazil.ORCID http://orcid.org/0009-0002-7499-8435
Larissa MarcondesUniversidade Federal do Paraná, Programa de Pós-Graduação em Enfermagem, Curitiba, PR, Brazil.ORCID http://orcid.org/0000-0002-8745-6486
Ruth Natalia Teresa TurriniUniversidade de São Paulo, Escola de Enfermagem, Departamento de Enfermagem Médico-Cirúrgica, São Paulo, SP, Brazil.ORCID http://orcid.org/0000-0002-4910-7672
Paulo Ricardo Bittencourt GuimarãesUniversidade Federal do Paraná, Departamento de Estatística, Curitiba, PR, Brazil.ORCID http://orcid.org/0000-0002-9852-6777
Maria de Fátima MantovaniUniversidade Federal do Paraná, Programa de Pós-Graduação em Enfermagem, Curitiba, PR, Brazil.ORCID http://orcid.org/0000-0001-7961-8273
Luciana de Alcantara NogueiraUniversidade Federal do Paraná, Programa de Pós-Graduação em Enfermagem, Curitiba, PR, Brazil.ORCID http://orcid.org/0000-0002-5985-7418
Luciana Puchalski KalinkeUniversidade Federal do Paraná, Programa de Pós-Graduação em Enfermagem, Curitiba, PR, Brazil.ORCID http://orcid.org/0000-0003-4868-8193

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo evaluate the effect of Bach Flower Remedies Therapy on the hope and quality of life of people with advanced cancer.

methodRandomized, triple-blind (1:1) clinical trial in a high-complexity public hospital in the Southern region of Brazil. Ninety-nine participants were allocated to either the intervention group (solution with nine flower essences) or the placebo group (Hydro-brandy solution). Both groups used four drops orally, four times a day, for 120 days, with monthly follow-up. Hope measured by the Herth Hope Index, quality of life through Functional Assessment of Chronic Illness Therapy - Palliative Care.

resultsIn the flower remedies group (n = 50), hope varied from 43.44/48 to 44.53/48 and in the placebo group (n = 49) from 41.67/48 to 44.29/48, a significant increase over time (p = 0.024), with no difference between groups (p = 0.977). Quality of life ranged from 141.39/184 to 150.60/184 in the flower remedies group, and from 133.76/184 to 148.96/184 in the placebo group, with no significant difference between groups (p = 0.230) or time (p = 0.240).

conclusionAlthough not statistically significant, there was a slight increase in life expectancy and quality of life, highlighting the importance of non-pharmacological therapies in evidence-based palliative care practice. BRAZILIAN REGISTRY OF CLINICAL TRIALS: RBR-8q6z6kq.

Indexed as

FlowersHopeNeoplasmsPhytotherapyQuality of LifeAdultAgedBrazilFemaleHumansMaleMiddle AgedPalliative Care

Identifiers

PMID42485509
PMCPMC13390996

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.