Evidence map›Paper›PMID 42485327›Full record

SynthesisThe Gerontologist2026

Effectiveness of psychosocial interventions for anticipatory grief in informal caregivers for people living with dementia: a systematic review and meta-analysis.

Cong Fu, Marques Shek Nam Ng, Wai Tong Chien, Thi Nhi Vo, Stinne Glasdam

Abstract readSystematic ReviewMeta-Analysis
In one paragraph

Synthesis in The Gerontologist, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Cong FuIntegrative Health Research, Department of Health Sciences, Faculty of Medicine, Lund University, Lund, Sweden.ORCID 0000-0002-0312-4266
Marques Shek Nam NgThe Nethersole School of Nursing, Faculty of Medicine, The Chinese University of Hong Kong, New Territories, Hong Kong.ORCID 0000-0002-1520-1783
Wai Tong ChienThe Nethersole School of Nursing, Faculty of Medicine, The Chinese University of Hong Kong, New Territories, Hong Kong.ORCID 0000-0001-5321-5791
Thi Nhi VoThe Nethersole School of Nursing, Faculty of Medicine, The Chinese University of Hong Kong, New Territories, Hong Kong.
Stinne GlasdamIntegrative Health Research, Department of Health Sciences, Faculty of Medicine, Lund University, Lund, Sweden.ORCID 0000-0002-0893-3054

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

objectivesPsychosocial interventions support informal caregivers of people with dementia, but their impact on anticipatory grief and related health outcomes remains unclear. This review examines the effectiveness of different psychosocial approaches in addressing these outcomes. RESEARCH DESIGN AND

methodsA systematic review and meta-analysis were conducted following PRISMA guidelines and registered in PROSPERO (CRD42024629388). Eight databases were searched from inception to January 10, 2025. Two reviewers independently screened studies, assessed bias, and extracted data. Leave-one-out sensitivity and subgroup analyses addressed heterogeneity. Evidence quality was assessed using the GRADEpro Guideline Development Tool.

resultsEleven interventional studies were included. Psychosocial interventions (n = 6) had no significant short-term (<1 month: SMD = -0.57, 95% CI: [-1.14, 0.01], p = .05, I2 = 85%) or medium-term (1-6 months; SMD = -0.76, 95% CI: [-1.99, 0.46], p = .22, I2 = 88%, n = 3) effect on anticipatory grief but showed improvement in the long term (≥6 months; MD = -0.41, 95% CI: [-0.62, -0.20], p = .0001, I2 = 0%, n = 2). Short-term reductions in depression were also observed, with no significant effects in other outcomes. Subgroup analyses did not identify frameworks or delivery methods linked to better outcomes. The GRADEpro rated the evidence as "Low" to "Very Low." DISCUSSION AND IMPLICATIONS: Overall, psychosocial interventions have limited short- and medium-term impact on anticipatory grief. Individual, technology-mediated cognitive-behavioral approaches may improve anticipatory grief in long term, but evidence is limited. Further research should clarify the concept of anticipatory grief and evaluate interventions in large, rigorous RCTs. CLINICAL TRIAL REGISTRATION NUMBER: CRD42024629388.

Indexed as

CaregiversDementiaGriefPsychosocial InterventionHumansSocial SupportDementia caregivingEmotional distressMultiple lossesSupport for family member

Identifiers

PMID42485327
PMCPMC13534144

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.