Evidence map›Paper›PMID 42485039›Full record

ArticleJAMA network open2026

Life-Space Mobility Trajectories After Elective Surgery in Older Adults.

Nai-Wen Ku, Nelly Toledano, Nicholas Legacy, Keying Xu, Duminda N Wijeysundera, Kristen R Haase, Eric Pitters, Fay Bennie, Anne Stephens, Gianni R Lorello and 20 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in JAMA network open, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

30 authors.

Nai-Wen KuLawrence Bloomberg Faculty of Nursing, University of Toronto, Toronto, Ontario, Canada.
Nelly ToledanoLawrence Bloomberg Faculty of Nursing, University of Toronto, Toronto, Ontario, Canada.
Nicholas LegacyLawrence Bloomberg Faculty of Nursing, University of Toronto, Toronto, Ontario, Canada.
Keying XuApplied Health Research Centre, Li Ka Shing Knowledge Institute, St Michael's Hospital, Unity Health Toronto, Toronto, Ontario, Canada.
Duminda N WijeysunderaDepartment of Anesthesia, Unity Health-St Michael's Hospital, Toronto, Ontario, Canada.
Kristen R HaaseSchool of Nursing, University of British Columbia, Vancouver, British Columbia, Canada.
Eric PittersLawrence Bloomberg Faculty of Nursing, University of Toronto, Toronto, Ontario, Canada.
Fay BennieLawrence Bloomberg Faculty of Nursing, University of Toronto, Toronto, Ontario, Canada.
Anne StephensLawrence Bloomberg Faculty of Nursing, University of Toronto, Toronto, Ontario, Canada.
Gianni R LorelloDepartment of Anesthesiology and Pain Medicine, University of Toronto, Toronto, Ontario, Canada.
Kerry KuluskiInstitute of Health Policy, Management and Evaluation, Dalla Lana School of Public Health, University of Toronto, Toronto, Ontario, Canada.
Daniel I McIsaacDepartments of Anesthesiology and Pain Medicine, The Ottawa Hospital and University of Ottawa, Ottawa, Ontario, Canada.
Tyler R ChesneyDivision of General Surgery, Department of Surgery, University of Toronto, Toronto, Ontario, Canada.
Naveed SiddiquiDepartment of Anesthesia and Pain Management, Sinai Health, University of Toronto, Toronto, Ontario, Canada.
Karim S LadhaDepartment of Anesthesia, Unity Health-St Michael's Hospital, Toronto, Ontario, Canada.
C David MazerDepartment of Anesthesia, Unity Health-St Michael's Hospital, Toronto, Ontario, Canada.
Noah CramptonDepartment of Family Medicine, Toronto Western Hospital, University Health Network, Toronto, Ontario, Canada.
Stuart A McCluskeyDepartment of Anesthesiology and Pain Medicine, University of Toronto, Temerty Faculty of Medicine, University of Toronto, and Department of Anesthesia and Pain Management, Toronto General Hospital, University Health Network, Toronto, Ontario, Canada.
Matteo ParottoDepartment of Anesthesiology and Pain Medicine, University of Toronto, Temerty Faculty of Medicine, University of Toronto, and Department of Anesthesia and Pain Management, Toronto General Hospital, University Health Network, Toronto, Ontario, Canada.
Lisa Del GiudiceDepartment of Family and Community Medicine, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada.
Angela JerathDepartment of Anesthesiology and Pain Medicine, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Ontario, Canada.
Janet van VlymenDepartment of Anesthesiology and Perioperative Medicine, Kingston Health Science Centre, Kingston, Ontario, Canada.
Su-Yin MacDonellDepartment of Anesthesia, Providence Health Care (St Paul's and Mount St Joseph Hospitals), Vancouver, British Columbia, Canada.
Melinda DavisDepartment of Anesthesiology, Perioperative, and Pain Medicine, University of Calgary, Calgary, Alberta, Canada.
Alexander J GregoryDepartment of Anesthesiology, Perioperative and Pain Medicine and Libin Cardiovascular Institute, University of Calgary, Calgary, Alberta, Canada.
Eric JacobsohnDepartment of Anesthesiology, Pain and Perioperative Medicine, University of Manitoba, Winnipeg, Manitoba, Canada.
Katherine S McGiltonLawrence Bloomberg Faculty of Nursing, University of Toronto, Toronto, Ontario, Canada.
Emily HladkowiczOttawa Hospital Research Institute, Acute Care Research Program, Ottawa, Ontario, Canada.
Shabbir M H AlibhaiDepartment of Medicine and Department of Supportive Care, Princess Margaret Cancer Centre, University Health Network, and Faculty of Medicine and Institute for Health Policy, Management and Evaluation, University of Toronto, Toronto, Ontario, Canada.
Martine PutsLawrence Bloomberg Faculty of Nursing, University of Toronto, Toronto, Ontario, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Importance: The number of older adults living with frailty who undergo surgery is rapidly increasing worldwide. Life-space mobility (LSM) can capture physical and social dimensions of recovery and has been linked to functional decline and reduced quality of life. Objective: To examine postoperative recovery using LSM among older adults living with frailty and to identify factors associated with restricted mobility and readmission. Design, Setting, and Participants: This cohort study within the larger Functional Improvement Trajectories After Surgery study used a convergent mixed-methods exploratory design. Seventeen hospitals across Canada included older adults aged 65 years or older with a clinical frailty score (CFS) of 3 or more who underwent major elective noncardiac surgery from March 2021 to June 2023. Data were analyzed from September to October 2025. Exposure: Elective noncardiac surgery among older adults. Main Outcomes and Measures: LSM (range 0-120, with higher scores indicating more mobility) was measured at 1 to 2 months and 6 months postoperatively, with retrospective presurgery LSM captured at 1 to 2 months. Multivariable linear mixed-effects models and multivariable mixed-effects logistic regression were used to identify factors associated with LSM trajectories, restricted mobility (ie, LSM < 60), and hospital readmission. Results: This study included 204 participants (mean [SD] age, 72.8 [5.6] years; 108 males [53%]). The mean (SD) LSM was 65.1 (26.7) presurgery, 56.6 (26.7) at 2 months postsurgery, and 64.9 (25.9) at 6 months postsurgery. Eighty participants (39.2%) had restricted mobility presurgery, 114 (56.4%) at 2 months postsurgery, and 84 (41.2%) at 6 months postsurgery. Restricted mobility was associated with being a woman (odds ratio [OR], 4.72; 95% CI, 2.27-9.84), greater frailty (OR, 10.42; 95% CI, 3.56-30.49), and concurrent need for support from formal or informal caregivers (OR, 5.43; 95% CI, 2.72-10.86). Elevated-risk surgery was associated with hospital readmission at 6 months (OR, 3.18; 95% CI, 1.48-7.25). Conclusions and Relevance: In this nested cohort study, mean LSM recovered by 6 months postsurgery, but 41% of older adults still had restricted mobility. Being a woman, having greater frailty, and needing support from caregivers were associated with poor recovery. Integrating life-space assessments into individualized perioperative care planning may enhance evaluation of functional recovery, inform shared decision-making, and guide support strategies.

Indexed as

Elective Surgical ProceduresFrail ElderlyFrailtyMobility LimitationActivities of Daily LivingAgedAged, 80 and overCanadaCohort StudiesFemaleHumansMalePatient ReadmissionQuality of LifeRetrospective Studies

Identifiers

PMID42485039
PMCPMC13392812

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.