Evidence map›Paper›PMID 42484990›Full record

ArticleSpine deformity2026

One in five cases of spondylolysis are missed on MRI: a retrospective analysis of pediatric patients with back pain.

Prudhvi Kodali, James P Caruso, George Michael, Andy Liu, Suhas Etigunta, Vivien Chan, David L Skaggs, Kenneth D Illingworth

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Article in Spine deformity, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

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2citing papers in PubMed
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3 · Its place in the literature

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2 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Prudhvi KodaliCedars Sinai Medical Center, Los Angeles, California, USA.
James P CarusoCedars Sinai Medical Center, Los Angeles, California, USA.
George MichaelCedars Sinai Medical Center, Los Angeles, California, USA.
Andy LiuCedars Sinai Medical Center, Los Angeles, California, USA.
Suhas EtiguntaCedars Sinai Medical Center, Los Angeles, California, USA.
Vivien ChanAlberta Children's Hospital, University of Calgary, Calgary, AB, Canada.
David L SkaggsCedars Sinai Medical Center, Los Angeles, California, USA.
Kenneth D IllingworthCedars Sinai Medical Center, Los Angeles, California, USA. Kenneth.Illingworth@csmc.edu.ORCID http://orcid.org/0000-0001-7088-5906

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionLumbar spondylolysis is a common cause of pediatric low back pain. Although CT is highly sensitive, MRI is often used first to avoid radiation. Pars defects may be missed on MRI, potentially delaying care. The frequency and clinical impact of these missed diagnoses remain poorly defined. The purpose of this study is to assess how often spondylolysis is missed on MRI reports.

methodsA single-institution retrospective review was performed of pediatric patients with lumbar spondylolysis treated between 2021 and 2024. All patients underwent MRI for evaluation of low back pain. MRI reports were reviewed to determine whether spondylolysis was identified. STIR sequences were examined for pars hyperintensity. Demographic variables, radiologist fellowship training, and time from symptom onset to orthopaedic treatment were recorded. Groups with and without missed MRI diagnoses were compared using independent t tests and Chi-square analyses.

resultsAmong 102 patients with spondylolysis, 21 (20.6%) had MRI reports that failed to identify the pars defect. Among missed cases, 13/21 (61.9%) demonstrated hyperintense pars signal on STIR sequences that was not reported. Patients with missed MRI diagnoses had significantly longer delays to treatment initiation compared with those correctly diagnosed (10.6 ± 7.6 vs 6.7 ± 6.4 months from symptom onset; p = 0.042). Fellowship-trained musculoskeletal or neuroradiologists identified spondylolysis in 82.3% of cases compared with 64.7% among non-fellowship-trained radiologists, though this difference was not statistically significant (p = 0.100).

conclusionLumbar spondylolysis is missed in ~ 20% of MRI reports, of which the majority demonstrate pathognomonic edema on the STIR sequence. This was associated with significant delays in treatment. There should be a high index of suspicion in pediatric patients with clinical histories suggestive of spondylolysis, even if MRI reports are negative.

Indexed as

Delayed diagnosisDiagnostic accuracyMagnetic resonance imaging (MRI)Pars interarticularis defectPediatric low back painSpondylolysis

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.