Evidence map›Paper›PMID 42484987›Full record

ReviewBiometals : an international journal on the role of metal ions in biology, biochemistry, and medicine2026

Metal dependent regulation of sesquiterpene biosynthesis and redox signalling in Santalum album.

P Ravi Raja Simman, A Balasubramanian, B Sivakumar, Balaji Kannan, K P Ragunath, P Rajendran, P Hemalatha, S Navaneetha Krishnan, R Adithiyan, S Ashwin Kumar and 1 more

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In one paragraph

Review in Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

P Ravi Raja SimmanForest College and Research Institute, Tamil Nadu, Mettupalayam, 641 301, India.
A BalasubramanianForest College and Research Institute, Tamil Nadu, Mettupalayam, 641 301, India. balasubramanian.a@tnau.ac.in.
B SivakumarDepartment of Silviculture and NRM, Forest College and Research Institute, Tamil Nadu, Mettupalayam, 641 301, India.
Balaji KannanDepartment of Soil and Water Conservation Engineering, TNAU, Tamil Nadu, Coimbatore, 641 003, India.
K P RagunathCentre for Water & Geospatial Studies, TNAU, Tamil Nadu, Coimbatore, 641 003, India.
P RajendranDepartment of Silviculture and NRM, Forest College and Research Institute, Tamil Nadu, Mettupalayam, 641 301, India.
P HemalathaDepartment of Forest Products and Utilization, Forest College and Research Institute, Tamil Nadu, Mettupalayam, 641 301, India.
S Navaneetha KrishnanDepartment of Silviculture and NRM, Forest College and Research Institute, Tamil Nadu, Mettupalayam, 641 301, India.
R AdithiyanForest College and Research Institute, Tamil Nadu, Mettupalayam, 641 301, India.
S Ashwin KumarForest College and Research Institute, Tamil Nadu, Mettupalayam, 641 301, India.
R V SundarrajanDepartment of Silviculture and NRM, Forest College and Research Institute, Tamil Nadu, Mettupalayam, 641 301, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Trace metal ions regulate enzymatic catalysis, redox homeostasis, and xenobiotic metabolism across biological systems. This article examines the role of metal ions in governing sesquiterpene biosynthesis and redox signalling in Santalum album from a bioinorganic perspective. Current evidence in this review indicates that the formation of α- and β-santalol depends on magnesium-coordinated terpene synthases and iron-containing cytochrome P450 monooxygenases. In these systems, Mg

Indexed as

MetalsSantalumSesquiterpenesAlkyl and Aryl TransferasesCytochrome P-450 Enzyme SystemIronOxidation-ReductionSignal TransductionAlkyl and Aryl TransferasesCytochrome P-450 Enzyme SystemIronMetalsSesquiterpenesterpene synthaseCytochrome P450ICP-MSIron homeostasisMagnesium coordinationMetallomicsMetal toxicityTerpene synthase

Identifiers

PMID42484987

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.