Evidence map›Paper›PMID 42484963›Full record

ReviewCurrent neurology and neuroscience reports2026

Environmental Exposures and Stroke Risk: Converging Pathways, Unequal Burdens, and Prevention Opportunities.

Muaz Ali, Whitney Mayberry, Rebecca Achey, Jukka Putaala, Amre Nouh

Abstract readReview
In one paragraph

Review in Current neurology and neuroscience reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Muaz AliDepartment of Neurology, Cleveland Clinic Florida, Weston, FL, USA.ORCID 0009-0005-1138-4892
Whitney MayberryDepartment of Neurology, Cleveland Clinic Florida, Weston, FL, USA.ORCID 0000-0001-8044-2025
Rebecca AcheyDepartment of Neurosurgery, Cleveland Clinic Foundation, Cleveland, OH, USA.
Jukka PutaalaDepartment of Neurology, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.ORCID 0000-0002-6630-6104
Amre NouhDepartment of Neurology, Cleveland Clinic Foundation, Cleveland, OH, USA. NOUHA@ccf.org.ORCID 0009-0003-4086-2211

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purpose of reviewTo synthesize recent evidence on how environmental exposures influence stroke risk, with emphasis on air pollution, thermal stress, circadian and occupational disruption, built and social environments, and selected toxicants. RECENT

findingsLong-term and episodic air pollution, especially fine particulate matter with aerodynamic diameter ≤ 2.5 μm (PM₂.₅) and wildfire smoke, remain most consistently associated with stroke risk. Extreme heat combined with heat-humidity metrics is emerging as an important acute stroke trigger. Noise, artificial light at night, shift work, and long working hours show smaller but plausible associations, while greener and more walkable environments may be modestly protective. Social and structural disadvantage clusters, multiple exposures and inequities play an integrated role in risk and prevention. Environmental determinants are increasingly relevant to stroke risk. The strongest current links are realted to pollution, heat, sleep, and work disruption, as well as environmental inequity. Future research should move beyond single-exposure models toward combined-exposure as well as intervention-focused approaches.

Indexed as

Environmental ExposureStrokeAir PollutionHumansRisk FactorsAir pollutionClimate changeEnvironmental exposuresExposomeSocial determinants of healthStroke

Identifiers

PMID42484963
PMCPMC13391753

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.