ArticleTropical animal health and production2026
Periparturient coenzyme Q10 administration: effects on immunity, milk quality, and growth performance in sheep.
Article in Tropical animal health and production, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This study investigated the effects of Coenzyme Q10 (CoQ10) oral administration on biochemical, immunological, microbiological, and productive parameters in sheep. Forty Barki ewes (3.5 ± 0.6 years; 47.5 ± 0.5 kg; 91-96 days of gestation) were randomly assigned to a control group (standard diet) and a treatment group (standard diet + 2 mg CoQ10 /kg BW). The experiment was conducted from late gestation through four weeks postpartum. CoQ10 administration increased serum total protein (5.49 vs. 5.01 g/dL) and globulin (3.00 vs. 2.49 g/dL) at parturition (p < 0.01), along with higher immunoglobulin A (IgA) (92.60 vs. 74.20 ng/mL) and glutathione peroxidase (GPx) activity (28.55 vs. 19.15 U/mL). In lambs of CoQ10-treated ewes, total protein (5.41 vs. 4.52 g/dL), IgA (137.10 vs. 88.01 ng/mL), and total antioxidant capacity (TAC) (43.96 vs. 32.11 mM/L) were higher (p < 0.05). Colostrum and milk from treated ewes showed higher solids-not-fat (15.41 vs. 12.32%, p < 0.01) and fat content (up to 7.7 vs. 5.7%, p < 0.01), with consistently higher immunoglobulins and reduced microbial incidence. Milk yield was higher in treated ewes, with a significant increase at week 4. Lambs of CoQ10-treated ewes had consistently higher body weight at all measured time points (p < 0.05). In conclusion, periparturient CoQ10 administration enhanced antioxidant status, immune-related parameters, milk quality, and growth performance. These findings support CoQ10 as a potential management strategy to alleviate periparturient stress and improve productivity in sheep production systems. Further studies are needed to optimize dosage and evaluate long-term effects under commercial conditions.
Indexed as
Identifiers
42484932What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.