ArticleInternational ophthalmology2026
Large optical zone transepithelial PRK: refractive and aberration outcomes.
Article in International ophthalmology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
purposeTo assess refractive outcomes and corneal higher-order aberration changes following transepithelial photorefractive keratectomy (TPRK) performed with large optical zones.
methodsData from 222 eyes of 112 myopic patients undergoing single-step TPRK with Smart Pulse Technology were reviewed retrospectively. Eyes were classified according to programmed optical zone diameter into large optical zone (LOZ, 6.6-7.0 mm; n = 57) and extra-large optical zone (XLOZ, 7.1-7.5 mm; n = 165) groups. Refractive results, safety and efficacy indices, and corneal wavefront aberrations were assessed at the 6-month follow-up.
resultsRefractive accuracy was high, with 81.1% of eyes within ± 0.50 D and 98.2% within ± 1.00 D of target refraction at 6 months. Safety and efficacy were comparable between the LOZ and XLOZ groups, and no clinically significant haze was observed. Corneal higher-order aberrations increased more in the LOZ group, whereas smaller changes and a slight reduction in coma were observed in the XLOZ group (p < 0.05).
conclusionsTPRK performed with large optical zones demonstrated excellent refractive predictability, safety, and efficacy. The use of extra-large optical zones was associated with smaller increases in corneal higher-order aberrations, suggesting that larger optical zones may help preserve postoperative optical quality after TPRK.
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