ArticleInnere Medizin (Heidelberg, Germany)2026
[Symptom burden in chronic kidney disease-nephrological assessment compared to patients' perspectives (SOMA.CK study)].
Article in Innere Medizin (Heidelberg, Germany), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
backgroundIndividuals with nondialysis chronic kidney disease (ND-CKD) often report high somatic symptom burden, though traditional clinical approaches associate symptom burden only with advanced disease stages.
objectivesThis study compared the symptom burden in ND-CKD as perceived by physicians and patients. MATERIALS AND
methodsIn a German-wide online survey, nephrologists identified the three most common symptoms and the mean symptom burden in CKD using an adapted version of the Chronic Kidney Disease Symptom Burden Index (CKD-SBI). Their assessments were compared with patients' self-reports (CKD-SBI) from the SOMA.CK study.
resultsResponses from N = 108 nephrologists (average professional experience = 14.3 years) were compared with responses from N = 222 individuals with ND-CKD (average age = 61.22 years, standard deviation [SD] = 14.90). Nephrologists most frequently named fatigue (69.44%), oedema (38.89%) and arterial hypertension (35.19%), while patients named nycturia (74.30%), fatigue (61.30%) and sleeping problems (47.30%). Nephrologists significantly overestimated the overall symptom burden and the symptom burden of five single symptoms, while they assessed the severity of 12 symptoms lower and 15 symptoms as comparable.
conclusionA discrepancy between the symptom burden reported by physicians and patients with ND-CKD was shown. Thus, giving greater consideration to the patients' perspectives in symptom assessment is recommended.
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