ArticleJapanese journal of radiology2026
Safety of extensive mesenteric embolization using quick-soluble gelatin sponge particles: an experimental canine study.
Article in Japanese journal of radiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors.
Funding
Abstract
purposeTranscatheter arterial embolization is an essential treatment for lower gastrointestinal bleeding; however, embolization of multiple vasa recta carries a substantial risk of bowel infarction. This study aimed to evaluate the safety of quick-soluble gelatin sponge particles (QS) compared with conventional gelatin sponge particles (GS) in a canine model of superior mesenteric artery branch embolization. MATERIALS AND
methodsThis study planned to include 10 Beagle dogs. The entire ileocolic artery and its vasa recta were non-selectively embolized to create a stringent ischemic environment. DSA was performed at 15, 30, and 60 min after embolization and on days 1 and 7 post-embolization. Dogs were randomly assigned to receive QS (n = 5) or GS (n = 5). The primary outcome was 7-day survival. Secondary outcomes included angiographic recanalization, as well as macroscopic and histopathological evaluation of intestinal necrosis.
resultsGiven the first two mortality cases in the GS group, further enrollment in the GS group was halted. All five dogs in the QS group survived the 7-day observation period, demonstrating a significantly higher survival rate than the GS group (100% [5/5] vs. 0% [0/2]; P = 0.048). Sequential angiography showed progressive recanalization beginning within 15-30 min post-embolization in the QS group, whereas no recanalization occurred in the GS group. Macroscopic and histopathological examination demonstrated preservation of intestinal tissue in the QS group, whereas the GS group showed severe intestinal ischemia with widespread hemorrhagic necrosis.
conclusionIn this proof-of-concept canine study, extensive mesenteric embolization using QS appeared to facilitate rapid blood flow restoration and complete histopathological preservation of the bowel. These hypothesis-generating findings warrant confirmation in larger studies.
Indexed as
Identifiers
42484839What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.