ArticleJournal of molecular modeling2026
Evolutionary and physics-guided modulation of Ca
Article in Journal of molecular modeling, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Hierarchical Organization of Evolutionary Constraint in Duplicated EF-Hand Motifs.Journal of molecular evolution · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
contextPrecise tuning of Ca
methodsEvolutionary constraints were inferred from vertebrate ortholog sequences using a Potts-model framework implemented in GREMLIN. Physics-based energetic screening was performed with PyRosetta using the ref2015 energy function, and molecular dynamics simulations were conducted using AMBER 2024 with the ff14SB force field, TIP3P solvent, Joung-Cheatham ion parameters, and a 12-6-4 Lennard-Jones Ca
Indexed as
Identifiers
42484751What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.