ReviewSleep & breathing = Schlaf & Atmung2026
Dise in osa: valuable tool or an overestimated technique? a systematized review.
Review in Sleep & breathing = Schlaf & Atmung, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
4 authors.
Funding
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Abstract
purposeDrug-Induced Sleep Endoscopy (DISE) is increasingly used to evaluate upper airway dynamics in obstructive sleep apnea patients (OSA). It enables real-time visualization of collapse and may support treatment selection; however, its true clinical impact and limitations remain controversial. This study aims to summarize the current evidence regarding the real role of DISE in OSA management.
methodsA structured literature review of the literature was conducted, focusing on key aspects of DISE, including its diagnostic utility, comparison with awake endoscopy, pharmacological agents used, effects on sleep architecture and muscle tone, the role of bispectral index, indications and contraindications, relevance in hypoglossal nerve stimulation selection, and its impact on surgical outcomes.
resultsDISE provides dynamic assessment of upper airway collapse, facilitating anatomical diagnosis and treatment personalization. It is useful in complex cases, treatment failures, and candidate selection for HNS. Commonly used agents -propofol, midazolam, and dexmedetomidine- differ in their effects on sleep architecture and muscle tone, none fully reproducing natural sleep. Importantly, current evidence shows no consistent improvement in surgical outcomes when DISE is used compared with awake evaluation alone. Additionally, variability in protocols and interpretation limits reproducibility.
conclusionsDISE is a valuable complementary tool for anatomical localization of upper airway collapse and treatment planning in OSA. However, it cannot replace polysomnography as the diagnostic gold standard and should be interpreted within a comprehensive clinical context. Further standardization and high-quality studies are needed to better define its role and optimize its clinical utility.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.