Evidence map›Paper›PMID 42484651›Full record

ReviewInfection and immunity2026

ABPs: diffusible antibacterial toxins secreted by and active against diverse gram-positive bacteria.

Jake Colautti, Daniel Mwangi, Joshua J Woodward, John C Whitney

Abstract readReview
In one paragraph

Review in Infection and immunity, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Jake ColauttiDepartment of Biochemistry and Biomedical Sciences, McMaster University, Hamilton, Ontario, Canada.ORCID 0000-0002-1461-0999
Daniel MwangiDepartment of Microbiology, University of Washington, Seattle, Washington, USA.
Joshua J WoodwardDepartment of Microbiology, University of Washington, Seattle, Washington, USA.ORCID 0000-0002-4630-403X
John C WhitneyDepartment of Biochemistry and Biomedical Sciences, McMaster University, Hamilton, Ontario, Canada.ORCID 0000-0002-4517-8836

Funding

Listeria monocytogenes physiology and host pathogen interactionsR01AI116669 · NIAID · UNIVERSITY OF WASHINGTON · PI WOODWARD, JOSHUA · 2015 to 2024
$4.4M
NIAID NIH HHS R01 AI116669
6 · The paper itself

Abstract

Competition between organisms is a ubiquitous feature of life on Earth and a major driver of evolutionary innovation. As Earth's most diverse and abundant organisms, bacteria employ numerous strategies to inhibit the growth of competitors, ranging from the production of diffusible antibiotic metabolites to the secretion of sophisticated protein toxins. Although secreted antibacterial protein toxins have been extensively studied in gram-negative bacteria, analogous systems employed by gram-positive organisms remain comparatively poorly understood. Recent work has shed light on a widespread family of secreted protein toxins associated with co-secreted serine proteases that likely mediate interbacterial competition among gram-positive species. These systems, termed

Indexed as

Anti-Bacterial AgentsBacterial ToxinsGram-Positive BacteriaBacterial ProteinsSerine ProteasesAnti-Bacterial AgentsBacterial ProteinsBacterial ToxinsSerine Proteasesantibacterial proteinsgram-positive bacteriainterbacterial competitionpolymorphic toxins

Identifiers

PMID42484651
PMCPMC13460014

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.