ArticleJACC. Case reports2026
Diagnostically Challenging Cardiac Myxoma Presenting as Acute Myocardial Infarction.
Article in JACC. Case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
backgroundPrimary cardiac tumors are rare. Among them, myxomas are the most common, and clinical presentations can be variable. CASE SUMMARY: A 31-year-old woman presented with sudden-onset chest pain and syncope. The electrocardiogram demonstrated self-terminating ventricular tachycardia and inferior ST-segment elevation. She was found to have a left atrial myxoma with embolization to the coronary arteries and underwent successful emergency resection. DISCUSSION: The diagnosis of stress cardiomyopathy was ruled out by echocardiography. Angiography did show an abrupt change in vessel diameter between normal and diseased segments, which suggested type 2 spontaneous coronary artery dissection. However, the abnormal left atrial feeding vessel suggested an embolic phenomenon from a cardiac tumor. TAKE-HOME MESSAGES: This case is an unusual presentation of an embolizing left atrial myxoma presenting as acute myocardial infarction in a young woman. This highlights the importance of including left atrial myxoma in the differential diagnosis of acute coronary syndrome in young female patients.
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