Evidence map›Paper›PMID 42484567›Full record

ArticleJACC. Case reports2026

Early Single-Leaflet Device Attachment After TEER: Device Orientation in Complex Mitral Anatomy.

Charilila-Loukia Ververeli, Argyro Kalompatsou, Ioannis Kachrimanidis, Yannis Dimitroglou, Sotirios Tsalamandris, Maria Drakopoulou, Constantina Aggeli, Konstantinos Tsioufis, Konstantinos Toutouzas

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In one paragraph

Article in JACC. Case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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5 · Who and what money

Authors and funding

9 authors.

Charilila-Loukia Ververeli1st Department of Cardiology, Hippokrateio General Hospital, National and Kapodistrian University of Athens, Athens, Greece. Electronic address: harilila_med@hotmail.com.
Argyro Kalompatsou1st Department of Cardiology, Hippokrateio General Hospital, National and Kapodistrian University of Athens, Athens, Greece.
Ioannis Kachrimanidis1st Department of Cardiology, Hippokrateio General Hospital, National and Kapodistrian University of Athens, Athens, Greece.
Yannis Dimitroglou1st Department of Cardiology, Hippokrateio General Hospital, National and Kapodistrian University of Athens, Athens, Greece.
Sotirios Tsalamandris1st Department of Cardiology, Hippokrateio General Hospital, National and Kapodistrian University of Athens, Athens, Greece.
Maria Drakopoulou1st Department of Cardiology, Hippokrateio General Hospital, National and Kapodistrian University of Athens, Athens, Greece.
Constantina Aggeli1st Department of Cardiology, Hippokrateio General Hospital, National and Kapodistrian University of Athens, Athens, Greece.
Konstantinos Tsioufis1st Department of Cardiology, Hippokrateio General Hospital, National and Kapodistrian University of Athens, Athens, Greece.
Konstantinos Toutouzas1st Department of Cardiology, Hippokrateio General Hospital, National and Kapodistrian University of Athens, Athens, Greece.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSingle-leaflet device attachment (SLDA) is an uncommon but clinically significant complication of transcatheter edge-to-edge repair (TEER), associated with recurrent mitral regurgitation (MR). CASE SUMMARY: A 73-year-old man with heart failure and severe MR presented with progressive dyspnea despite optimal medical therapy. Imaging demonstrated complex degenerative mitral valve anatomy. TEER with a PASCAL P10 device achieved initial MR reduction and hemodynamic improvement. Early follow-up revealed SLDA with posterior leaflet detachment and recurrent severe MR. A bailout TEER with implantation of a second PASCAL Ace device restored leaflet coaptation and stabilized the initial device. DISCUSSION: This case highlights the importance of early imaging surveillance and suggests that device orientation may influence leaflet insertion in complex anatomy. Conventional clocking strategies, such as 11-5 orientation, may not ensure optimal leaflet engagement in all patients. TAKE-HOME MESSAGES: Device orientation should be individualized in complex mitral anatomy. Early SLDA can be effectively managed with imaging-guided bailout TEER.

Indexed as

mitral regurgitationPASCALsingle-leaflet device attachmentTEERtranscatheter edge-to-edge repairtransesophageal echocardiography

Identifiers

PMID42484567
PMCPMC13531206

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