Evidence map›Paper›PMID 42484543›Full record

ArticleGeriatrics & gerontology international2026

Adverse Childhood Experiences and Social Frailty Trajectory Among Middle-Aged and Older Adults: A Network Analysis From a Population-Based Sample.

Xue Wang, Huaxin Si, Yanyan Li, Jiaqi Yu, Wendie Zhou, Hejing Chen, Cuili Wang

Abstract read
In one paragraph

Article in Geriatrics & gerontology international, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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0cells of the map it votes in
1citing papers in PubMed
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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Xue WangSchool of Nursing, Peking University, Beijing, China.
Huaxin SiSchool of Nursing, Peking University, Beijing, China.ORCID https://orcid.org/0000-0003-0103-6868
Yanyan LiSchool of Nursing, Peking University, Beijing, China.
Jiaqi YuSchool of Nursing, Peking University, Beijing, China.
Wendie ZhouSchool of Nursing, Peking University, Beijing, China.
Hejing ChenSchool of Nursing, Peking University, Beijing, China.
Cuili WangSchool of Nursing, Peking University, Beijing, China.ORCID https://orcid.org/0000-0002-8496-5621

Funding

National Natural Science Foundation of China 72274009
6 · The paper itself

Abstract

objectivesLife course theory posits that adverse childhood experiences (ACEs) exert lasting influences on health. However, their associations with the social frailty trajectory remain understudied in middle and later life.

methodsThis study utilized data from the China Health and Retirement Longitudinal Study (2011-2020). The social frailty trajectory was identified using group-based trajectory modeling (GBTM), while latent class analysis (LCA) classified distinct ACE patterns. Logistic regression models examined the associations between ACEs and social frailty trajectory. Additionally, network analysis was conducted to identify central nodes.

resultsThis study comprised 10 730 participants. Four patterns of social frailty trajectory were identified, namely persistently low then rising, persistently moderate then rising, initially moderate-high then rapidly declining, and persistently high then rising. Greater exposure to total ACEs (RRR = 1.11 [95% CI: 1.04, 1.17]; RRR = 1.16 [95% CI: 1.07, 1.26]; RRR = 1.25 [95% CI: 1.17, 1.34]), threat-related ACEs (RRR = 1.08 [95% CI: 1.001, 1.16]; RRR = 1.13 [95% CI: 1.02, 1.26]; RRR = 1.23 [95% CI: 1.12, 1.34]), deprivation-related ACEs (RRR = 1.22 [95% CI: 1.09, 1.35]; RRR = 1.30 [95% CI: 1.11, 1.51]; RRR = 1.42 [95% CI: 1.25, 1.61]), and the LCA-derived "household mental illness" cluster (RRR = 1.58 [95% CI: 1.18, 2.11]; RRR = 1.85 [95% CI: 1.26, 2.71]; RRR = 2.20 [95% CI: 1.59, 3.05]) was significantly associated with three disadvantaged patterns of social frailty trajectories compared to the persistently low then rising pattern. Network analysis revealed "household violence," "physical abuse," "household mental illness," and "bullying" as the most central nodes.

conclusionsThese findings implicate public health policies that promote early-life adversity screening, mental health interventions, and social resilience programs to maintain social functioning among middle-aged and older adults.

Indexed as

Adverse Childhood ExperiencesFrailtyAgedChinaFemaleHumansLatent Class AnalysisLongitudinal StudiesMaleMiddle AgedSocial Network Analysisadverse childhood experiencesaginggroup‐based trajectory modelslongitudinal studysocial frailty

Identifiers

PMID42484543
PMCPMC13390653

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.