Evidence map›Paper›PMID 42484355›Full record

ReviewApplied and environmental microbiology2026

Describing the persistence landscape for introducing microbes into complex communities.

Jason E McDermott, William C Nelson, Amy E Zimmerman, Winston Anthony, Devin Coleman-Derr, Joshua R Elmore, Tara Nitka, Ryan S McClure, Pubudu P Handakumbura, Adam M Guss and 2 more

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Applied and environmental microbiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Jason E McDermottBiological Sciences Division, Pacific Northwest National Laboratory, Richland, Washington, USA.ORCID 0000-0003-2961-2572
William C NelsonBiological Sciences Division, Pacific Northwest National Laboratory, Richland, Washington, USA.ORCID 0000-0002-1873-3929
Amy E ZimmermanBiological Sciences Division, Pacific Northwest National Laboratory, Richland, Washington, USA.ORCID 0000-0001-6709-8274
Winston AnthonyBiological Sciences Division, Pacific Northwest National Laboratory, Richland, Washington, USA.ORCID 0000-0001-6165-4700
Devin Coleman-DerrPlant Gene Expression Center, USDA-ARS, Albany, California, USA.
Joshua R ElmoreBiological Sciences Division, Pacific Northwest National Laboratory, Richland, Washington, USA.
Tara NitkaBiological Sciences Division, Pacific Northwest National Laboratory, Richland, Washington, USA.ORCID 0000-0001-9435-6515
Ryan S McClureBiological Sciences Division, Pacific Northwest National Laboratory, Richland, Washington, USA.ORCID 0000-0003-0573-6917
Pubudu P HandakumburaEnvironmental Molecular Sciences Division, Pacific Northwest National Laboratory, Richland, Washington, USA.
Adam M GussBiosciences Division, Oak Ridge National Laboratory, Oak Ridge, Tennessee, USA.ORCID 0000-0001-5823-5329
Travis J WheelerCollege of Pharmacy, University of Arizona, Tucson, Arizona, USA.
Robert G EgbertBiological Sciences Division, Pacific Northwest National Laboratory, Richland, Washington, USA.ORCID 0000-0002-9470-7124

Funding

U.S. Department of Energy Persistence Control of Engineered Functions in Complex Soil Microbiomes
6 · The paper itself

Abstract

Introducing non-native organisms into natural or designed microbial communities holds enormous potential but faces challenges in establishment, persistence, and containment. We propose the "persistence landscape"-the functional composition of a target microbiome that promotes or discourages engineered organism persistence. Building on existing ecological concepts, this framework predicts the fitness of introduced organisms. Application of this concept would enable controlled introduction of desired taxa and phenotypes, addressing pressing challenges in agronomy, biomanufacturing, and human health.

Indexed as

Microbiotacommunityengineered organismfitness landscapemicrobiomepersistence

Identifiers

PMID42484355
PMCPMC13488316

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.