ArticlemBio2026
The WalRK two-component system in
Justin J Zik, Zeyu Fu, Morgan N Price, Yujie Li, Qiao Yuan, Adam P Arkin, Adam M Deutschbauer, Josue Flores-Kim, Lok-To Sham
Abstract read
In one paragraphArticle in mBio, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literatureWho cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
4 · The recordCorrections and comments
5 · Who and what moneyAuthors and funding
9 authors.
Justin J ZikInfectious Diseases Translational Research Programme and Department of Microbiology and Immunology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.ORCID 0000-0003-0260-2446 Zeyu FuInfectious Diseases Translational Research Programme and Department of Microbiology and Immunology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.
Morgan N PriceEnvironmental Genomics and Systems Biology Division, Lawrence Berkeley National Laboratory, Berkeley, California, USA.ORCID 0000-0002-4251-0362 Yujie LiSchool of Chemistry, Chemical Engineering and Biotechnology (CCEB), Nanyang Technological University, Singapore, Singapore.
Qiao YuanSchool of Chemistry, Chemical Engineering and Biotechnology (CCEB), Nanyang Technological University, Singapore, Singapore.
Adam P ArkinEnvironmental Genomics and Systems Biology Division, Lawrence Berkeley National Laboratory, Berkeley, California, USA.
Adam M DeutschbauerEnvironmental Genomics and Systems Biology Division, Lawrence Berkeley National Laboratory, Berkeley, California, USA.
Josue Flores-KimDepartment of Biochemistry and Molecular Biotechnology, UMass Chan Medical School, Worcester, Massachusetts, USA.
Lok-To ShamInfectious Diseases Translational Research Programme and Department of Microbiology and Immunology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.ORCID 0000-0001-9047-0310 Funding
Discovery and characterization of bacterial cell envelope assembly and remodeling networks that modulate tolerance to antibioticsR35GM150669 · NIGMS · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI Josue Flores-Kim · 2023 to 2026
$1.7MMinistry of Education - Singapore MOE-T2EP30220-0012, MOE-T2EP30224-0012, MOE-T2EP30223-0002, MOE-T2EP10124-0001National Medical Research Council OFIRG23jan-0057National Research Foundation Singapore NRF-F-CRP-2024-0002NIGMS NIH HHS R35 GM150669NIH HHS 5R35GM150669
6 · The paper itselfAbstract
Capsular polysaccharide (CPS) is essential for IMPORTANCE:
Indexed as
Bacterial CapsulesBacterial ProteinsCell WallHistidine KinasePeptidoglycanStreptococcus pneumoniaeGene Expression Regulation, BacterialSignal TransductionTeichoic AcidsBacterial ProteinsHistidine KinasePeptidoglycanTeichoic Acidscapsular polysaccharideLCP ligasespeptidoglycan synthesisStreptococcus pneumoniaetwo-component systems
Identifiers
PMID42484351
PMCPMC13463712
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