Observational studyCritical care science2026
Cardiac surgery-associated acute kidney injury in a single healthcare system: a retrospective observational study.
Observational study in Critical care science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
1 citing paper in PubMed.
- Severity matters: reframing cardiac surgery-associated acute kidney injury.Critical care science · 2026Article
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo assess the incidence of cardiac surgery-associated acute kidney injury and to evaluate secondary outcomes, including 30-day mortality, prolonged mechanical ventilation, kidney replacement therapy, renal recovery, and length-of-stay metrics.
methodsThis retrospective observational study analyzed routinely recorded data from a single multi-hospital healthcare system, including all adult cardiac surgery intensive care unit patients between July 1st, 2021, and June 30, 2022. Cardiac surgery-associated acute kidney injury was stratified according to the KDIGO guidelines using serum creatinine. Urine output criteria were incorporated when available.
resultsCardiac surgery-associated acute kidney injury of any stage occurred in 16.7% of patients (stage 1 - 13.6%, stage 2 - 1.8%, and stage 3 - 1.3%). Thirty-day mortality had wide confidence intervals, with odds ratios of 20.8 (95%CI 3.8 - 114) and 93.6 (95%CI 23.4 - 375) for acute kidney injury stages 2 and 3, respectively, compared with stage 0. A total of 27.5% (52/189) of patients with cardiac surgery-associated acute kidney injury did not meet the strict definition of renal recovery at discharge. Median intensive care unit length of stay, average time on mechanical, and time to discharge were significantly longer in patients with cardiac surgery-associated acute kidney injury (p < 0.001).
conclusionCardiac surgery-associated acute kidney injury is a common postoperative complication associated with substantially increased mortality, prolonged ventilation, longer length of stay, and reduced renal recovery. These findings underscore the clinical importance of early identification, risk stratification, and perioperative management strategies to mitigate harm from acute kidney injury.
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