Evidence map›Paper›PMID 42484233›Full record

ArticleRevista brasileira de parasitologia veterinaria = Brazilian journal of veterinary parasitology : Orgao Oficial do Colegio Brasileiro de Parasitologia Veterinaria2026

Coinfection with Trypanosoma evansi and Hepatozoon felis in a free-ranging jaguar (Panthera onca) in the Pantanal biome, Brazil.

Brenda Maria Emanuela Silva Reis, Vithoria Eduarda Barboza Silva, Jordana Toqueto, Paloma Gabrieli da Silva, Stephanie Carrelo de Lima, Alda Izabel de Souza, Carlos Alberto do Nascimento Ramos

Abstract readCase Reports
In one paragraph

Article in Revista brasileira de parasitologia veterinaria = Brazilian journal of veterinary parasitology : Orgao Oficial do Colegio Brasileiro de Parasitologia Veterinaria, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Brenda Maria Emanuela Silva ReisUniversidade Federal de Mato Grosso do Sul - UFMS, Faculdade de Medicina Veterinária e Zootecnia - FAMEZ, Departamento de Patologia Clínica Veterinária, Campo Grande, MS, Brasil.ORCID http://orcid.org/0000-0002-5784-0727
Vithoria Eduarda Barboza SilvaUniversidade Federal de Mato Grosso do Sul - UFMS, Faculdade de Medicina Veterinária e Zootecnia - FAMEZ, Departamento de Medicina Veterinária Preventiva, Campo Grande, MS, Brasil.
Jordana ToquetoInstituto de Meio Ambiente de Mato Grosso do Sul - IMASUL, Centro de Reabilitação de Animais Silvestres - CRAS, Campo Grande, MS, Brasil.
Paloma Gabrieli da SilvaInstituto de Meio Ambiente de Mato Grosso do Sul - IMASUL, Centro de Reabilitação de Animais Silvestres - CRAS, Campo Grande, MS, Brasil.
Stephanie Carrelo de LimaUniversidade Federal de Mato Grosso do Sul - UFMS, Faculdade de Medicina Veterinária e Zootecnia - FAMEZ, Departamento de Patologia Clínica Veterinária, Campo Grande, MS, Brasil.
Alda Izabel de SouzaUniversidade Federal de Mato Grosso do Sul - UFMS, Faculdade de Medicina Veterinária e Zootecnia - FAMEZ, Departamento de Patologia Clínica Veterinária, Campo Grande, MS, Brasil.
Carlos Alberto do Nascimento RamosUniversidade Federal de Mato Grosso do Sul - UFMS, Faculdade de Medicina Veterinária e Zootecnia - FAMEZ, Departamento de Medicina Veterinária Preventiva, Campo Grande, MS, Brasil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Coinfection with Trypanosoma evansi and Hepatozoon felis represents a rare occurrence in wild felids, with no previous reports in Panthera onca. A free-ranging adult male jaguar weighing approximately 70 kg was examined after being rescued from wildfires in the Brazilian Pantanal (Corumbá, Mato Grosso do Sul). The initial hematological evaluation (D0) revealed mild anemia (PCV: 27.7%; reference: 30-45%), with Trypanosoma spp. trypomastigotes forms detected by direct microscopy. Treatment with diminazene aceturate (3.5 mg/kg, IM) was instituted on D1. On D5, microscopy revealed Hepatozoon felis gamonts within leukocytes, characterizing coinfection. Molecular analysis by PCR confirmed the presence of both agents in the D0 sample, with amplification products of approximately 600 bp (Hepatozoon spp.) and 196 bp (T. evansi), validating the microscopic diagnosis. Despite treatment and the absence of microscopically detectable parasitemia on D12, anemia persisted (PCV: 21.7%). The animal progressed to death on D19 during sedation for wound management. At necropsy, severe pulmonary involvement (bronchiolitis, alveolitis, and endogenous lipid pneumonia) compatible with smoke inhalation injury was observed. These findings highlight the importance of integrating hemoparasite surveillance into rehabilitation and conservation protocols for threatened felids in fire-affected ecosystems.

Indexed as

CoccidiosisCoinfectionPantheraTrypanosomaTrypanosomiasisAnimalsBrazilMale

Identifiers

PMID42484233
PMCPMC13445973

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.