Evidence map›Paper›PMID 42484112›Full record

ReviewArquivos de gastroenterologia2026

HELICOBACTER PYLORI BEYOND THE STOMACH: WHEN THE STORY CHANGES.

Bruno Squárcio Fernandes Sanches, Sandro Rodrigues Chaves, Frederico Passos Marinho, Guilherme Grossi Lopes Cançado, Daniel Antônio Albuquerque Terra, Maria Clara Freitas Coelho, Luiz Gonzaga Vaz Coelho

Abstract readReview
In one paragraph

Review in Arquivos de gastroenterologia, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Bruno Squárcio Fernandes SanchesNúcleo Brasileiro para o Estudo do Helicobacter pylori e Microbiota, São Paulo, SP, Brasil.ORCID http://orcid.org/0000-0003-0193-6292
Sandro Rodrigues ChavesRede Mater Dei de Saude, Belo Horizonte, MG, Brasil.ORCID http://orcid.org/0009-0001-9081-1522
Frederico Passos MarinhoUniversidade Federal de Minas Gerais, Hospital das Clínicas, Instituto Alfa de Gastroenterologia, Belo Horizonte, MG, Brasil.ORCID http://orcid.org/0000-0002-0107-3506
Guilherme Grossi Lopes CançadoUniversidade Federal de Minas Gerais, Hospital das Clínicas, Instituto Alfa de Gastroenterologia, Belo Horizonte, MG, Brasil.ORCID http://orcid.org/0000-0002-7824-2152
Daniel Antônio Albuquerque TerraUniversidade Federal de Minas Gerais, Hospital das Clínicas, Instituto Alfa de Gastroenterologia, Belo Horizonte, MG, Brasil.ORCID http://orcid.org/0000-0001-9691-6512
Maria Clara Freitas CoelhoFaculdade de Ciências Médicas de Minas Gerais, Belo Horizonte, MG, Brasil.ORCID http://orcid.org/0000-0001-8028-6114
Luiz Gonzaga Vaz CoelhoNúcleo Brasileiro para o Estudo do Helicobacter pylori e Microbiota, São Paulo, SP, Brasil.ORCID http://orcid.org/0000-0002-8721-7696

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundHelicobacter pylori (H. pylori) is well known as an etiological agent in several gastric diseases, including chronic gastritis, gastric and duodenal ulcers, gastric carcinoma, and lymphoma. Over the past decades, the understanding of its pathogenic role has evolved substantially, overcoming initial skepticism and establishing the bacterium as a major factor in gastroduodenal disease. However, epidemiological and experimental studies suggest that this chronic infection may also be associated with a variety of extragastric conditions.

objectiveThis review aims to evaluate the relationship between H. pylori infection and anemia, immune thrombocytopenic purpura, colorectal cancer, cardiovascular diseases, and neurological disorders.

methodsFor each association, the most recent evidence and current recommendations regarding the diagnosis and treatment of H. pylori infection during the clinical course of these conditions were assessed.

conclusionFurther prospective studies are needed to clarify whether these associations represent causal relationships with clinical relevance or merely statistical correlations, and to better determine the impact of H. pylori infection on extragastric diseases.

Indexed as

Cardiovascular DiseasesHelicobacter InfectionsHelicobacter pyloriAnemiaColorectal NeoplasmsHumansPurpura, Thrombocytopenic, Idiopathic

Identifiers

PMID42484112
PMCPMC13384413

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.