Evidence map›Paper›PMID 42483745›Full record

ArticleSmart medicine2026

Microfluidic Electrospray Microcapsules With Spatiotemporal Release of Asiatic Acid and Baicalein Nanocarriers for Wound Healing.

Zhiqiang Luo, Lingbao Zeng, Xinyu Zhu, Yuanjin Zhao

Abstract read
In one paragraph

Article in Smart medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Zhiqiang LuoSchool of Biological Science and Medical Engineering Southeast University Nanjing China.ORCID https://orcid.org/0000-0003-3158-1605
Lingbao ZengDepartment of Rheumatology and Immunology Nanjing Drum Tower Hospital School of Pharmacy, Nanjing University of Chinese Medicine Nanjing China.
Xinyu ZhuDepartment of Rheumatology and Immunology Nanjing Drum Tower Hospital School of Pharmacy, Nanjing University of Chinese Medicine Nanjing China.ORCID https://orcid.org/0009-0002-0309-7613
Yuanjin ZhaoSchool of Biological Science and Medical Engineering Southeast University Nanjing China.ORCID https://orcid.org/0000-0002-1171-8697

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Synergy therapy of Chinese herbs is an effective strategy for wound repair and its further development focuses on the chronological release of specific herbs with healing proceeding. Herein, we report a novel asiatic acid/baicalein nanocarrier integrated microcapsule with spatiotemporal release feature from microfluidic electrospray for wound healing. Benefiting from advantages of both nanocarrier formulation and integration capacity of microfluidic electrospray, synthesized baicalein-tannic acid nanoparticles are integrated into the shell of microcapsule while fabricated asiatic acid liposomes are located at the core region. This design enables chronological release: baicalein is first released to kill bacteria, followed by releasing asiatic acid liposomes to enhance cell migration and granulation tissue formation. In vitro tests confirm the excellent biocompatibility, antibacterial and pro-migration property of microcapsules. The results from in vivo wound healing studies showed the outcomes of reduced inflammation and accelerated wound closure in microcapsules-treated wounds. Therefore, it is believed that this herbal microcapsule with spatiotemporal and hierarchical release of baicalein and asiatic acid is an effective therapeutic platform for clinical wound treatment.

Indexed as

asiatic acidbaicaleinherbliposomemicrofluidicswound healing

Identifiers

PMID42483745
PMCPMC13387336

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.