ReviewEnvironment & health (Washington, D.C.)2026
Gaps between Laboratory Experiments and Real-World Exposure: Toxicological Assessment of Microplastics Is Based on Inadequate Evidence.
Review in Environment & health (Washington, D.C.), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
5 citing papers in PubMed.
- Effects of Aged Polymethylmethacrylate Microplastics on Physiological Biochemistry and Intestinal-Sediment Microbial Communities ofAnimals : an open access journal from MDPI · 2026Article
- Electronic Waste-Derived Nanomaterials: Environmental Release, Toxicity, and Public Health Risks.Nanomaterials (Basel, Switzerland) · 2026Review
- Gut-Microbial Responses to Acute Polyester Microplastic Exposure in Zebrafish: Dysbiosis, Opportunistic Bacteria, and Functional Impact.International journal of molecular sciences · 2026Article
- Reassessing Toxicity Claims of Micro- and Nanoplastics in Human Health Research.Environment & health (Washington, D.C.) · 2026Article
- Pathogenesis of Micro/Nanoplastics in Mammalian Systems: Gut to Systemic Multi-Organ Dysfunction.Research (Washington, D.C.) · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The global significance of microplastic (MP) toxicity assessment is widely acknowledged. Current studies have enhanced our understanding of the mechanisms behind MP toxicity; however, most research mainly focused on the toxicity of individual MPs, overlooking the environmental complexity that arises from the diversity of MPs and the combined effects of multiple pollutants. Furthermore, a notable gap exists in research concerning low-dose and long-term exposure, which significantly limits the relevance of current toxicity data for risk assessments. To address these challenges, we suggest a more thorough and logical approach to evaluating MP toxicity, including: enhancing the harmonization of methods for detecting and quantifying MPs in various environmental and biological matrixes; leveraging AI to simulate real environmental exposures and to predict the complex interactions between MPs and other environmental factors; and combining insights from environmental science, toxicology, materials science, and other relevant fields to bridge the gap between laboratory findings and real-world conditions. Collectively, these efforts could transform fragmented data into risk intelligence, delivering actionable governance solutions for global MP challenges.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.